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frd dihydrofolate reductase [ Aeromonas phage Ah1 ]

Gene ID: 65110649, updated on 11-Jan-2023

Summary

Gene symbol
frd
Gene description
dihydrofolate reductase
Locus tag
KNT77_gp189
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Aeromonas phage Ah1 (nat-host: Aeromonas hydrophila)
Lineage
Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Straboviridae; Cinqassovirus; Cinqassovirus ah1
Old locus tag
Ah1_00329
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Genomic context

Sequence:
NC_055733.1 (191486..192004, complement)

NC_055733.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene thymidylate synthase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene homing endonuclease Neighboring gene single-stranded DNA binding protein

General protein information

Preferred Names
dihydrofolate reductase
YP_010093058.1
  • Frd dihydrofolate reductase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_055733.1 Reference assembly

    Range
    191486..192004 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_010093058.1 dihydrofolate reductase [Aeromonas phage Ah1]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2H4YFB4
    Conserved Domains (1) summary
    cd00209
    Location:2140
    DHFR; Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5, ...