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IDH2 NAD-dependent isocitrate dehydrogenase [ Aspergillus luchuensis ]

Gene ID: 64958516, updated on 6-Jun-2024

Summary

Gene symbol
IDH2
Gene description
NAD-dependent isocitrate dehydrogenase
Locus tag
AKAW2_30510A
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Aspergillus luchuensis (strain: IFO 4308)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus
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Genomic context

Location:
chromosome: 3
Exon count:
6
Sequence:
Chromosome: 3; NC_054851.1 (1476109..1477693, complement)

Chromosome 3 - NC_054851.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables isocitrate dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in isocitrate metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
NAD-dependent isocitrate dehydrogenase
XP_041540957.1
  • COG:E;
    EggNog:ENOG410PFWG;
    InterPro:IPR004434,IPR024084,IPR019818;
    PFAM:PF00180;
    go_function: GO:0000287 - magnesium ion binding [Evidence IEA];
    go_function: GO:0004449 - isocitrate dehydrogenase (NAD+) activity [Evidence IEA];
    go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA];
    go_function: GO:0051287 - NAD binding [Evidence IEA];
    go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA];
    go_process: GO:0055114 - oxidation-reduction process [Evidence IEA]

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_054851.1 Reference assembly

    Range
    1476109..1477693 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041687032.1XP_041540957.1  NAD-dependent isocitrate dehydrogenase [Aspergillus luchuensis]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A146FS39
    Conserved Domains (1) summary
    cl00445
    Location:11385
    Iso_dh; Isocitrate/isopropylmalate dehydrogenase