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FAM90A12 family with sequence similarity 90 member A12 [ Homo sapiens (human) ]

Gene ID: 645879, updated on 10-Oct-2024

Summary

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Official Symbol
FAM90A12provided by HGNC
Official Full Name
family with sequence similarity 90 member A12provided by HGNC
Primary source
HGNC:HGNC:32260
See related
Ensembl:ENSG00000254229 MIM:613048; AllianceGenome:HGNC:32260
Gene type
protein coding
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM90A12P
Summary
FAM90A12 belongs to subfamily II of the primate-specific FAM90A gene family, which originated from multiple duplications and rearrangements (Bosch et al., 2007 [PubMed 17684299]). For background information on the FAM90A gene family, as well as information on the evolution of FAM90A genes, see FAM90A1 (MIM 613041).[supplied by OMIM, Jul 2010]
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Genomic context

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See FAM90A12 in Genome Data Viewer
Location:
8p23.1
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (8027636..8030646, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (11708430..11711440)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (7885158..7888168, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:7877325-7877826 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:7877827-7878326 Neighboring gene family with sequence similarity 90 member A11 Neighboring gene family with sequence similarity 90 member A24 Neighboring gene olfactory receptor family 7 subfamily E member 96 pseudogene Neighboring gene VPS51 pseudogene 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds. Bosch N, et al. Gene, 2008 Sep 1. PMID 18602769
  2. Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events. Bosch N, et al. Hum Mol Genet, 2007 Nov 1. PMID 17684299
  3. DNA sequence and analysis of human chromosome 8. Nusbaum C, et al. Nature, 2006 Jan 19. PMID 16421571

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General protein information

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Preferred Names
protein FAM90A12
Names
Putative protein FAM90A12
family with sequence similarity 90 member A12, pseudogene
putative protein FAM90A12P

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001423531.1 → NP_001410460.1  protein FAM90A12

    Status: INFERRED

    Source sequence(s)
    AC105233
    UniProtKB/Swiss-Prot
    A8MX19
    Related
    ENSP00000514268.1, ENST00000519497.3

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    8027636..8030646 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_018654717.1 Reference GRCh38.p14 PATCHES

    Range
    948377..951387 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    11708430..11711440
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_032086.2: Suppressed sequence

    Description
    NG_032086.2: This RefSeq was removed because it is now thought that this gene does encode a protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8MX19.1 GenPept UniProtKB/Swiss-Prot:A8MX19

Gene LinkOut

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Molecular Biology Databases
Research Materials