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LSP1P5 LSP1 pseudogene 5 [ Homo sapiens (human) ]

Gene ID: 645166, updated on 29-Oct-2024

Summary

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Official Symbol
LSP1P5provided by HGNC
Official Full Name
LSP1 pseudogene 5provided by HGNC
Primary source
HGNC:HGNC:50697
See related
Ensembl:ENSG00000288905 AllianceGenome:HGNC:50697
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in placenta (RPKM 6.5), urinary bladder (RPKM 4.2) and 23 other tissues See more
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Genomic context

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See LSP1P5 in Genome Data Viewer
Location:
1q21.1
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (144716079..144740806)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (143326556..143351287, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (148928313..148953054)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene lysine methyltransferase 2C pseudogene 1 Neighboring gene dopamine receptor D5 pseudogene 2 Neighboring gene RNA, 5S ribosomal pseudogene 59 Neighboring gene Sharpr-MPRA regulatory region 154 duplicate 3 Neighboring gene proton channel OTOP1-like Neighboring gene uncharacterized LOC105371216

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Down-Regulation of LOC645166 in T Cells of Ankylosing Spondylitis Patients Promotes the NF-κB Signaling via Decreasingly Blocking Recruitment of the IKK Complex to K63-Linked Polyubiquitin Chains. Yu HC, et al. Front Immunol, 2021. PMID 33717069, Free PMC Article
  2. Targeting the nuclear long noncoding transcript LSP1P5 abrogates extracellular matrix deposition by trans-upregulating CEBPA in keloids. Gu S, et al. Mol Ther, 2024 Jun 5. PMID 38553852,
  3. Human lymphocyte-specific pp52 gene is a member of a highly conserved dispersed family. May W, et al. Genomics, 1993 Mar. PMID 8468046
  4. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Dias Neto E, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10737800, Free PMC Article
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Targeting the nuclear long noncoding transcript LSP1P5 abrogates extracellular matrix deposition by trans-upregulating CEBPA in keloids.
    Title: Targeting the nuclear long noncoding transcript LSP1P5 abrogates extracellular matrix deposition by trans-upregulating CEBPA in keloids.
  2. Down-Regulation of LOC645166 in T Cells of Ankylosing Spondylitis Patients Promotes the NF-kappaB Signaling via Decreasingly Blocking Recruitment of the IKK Complex to K63-Linked Polyubiquitin Chains.
    Title: Down-Regulation of LOC645166 in T Cells of Ankylosing Spondylitis Patients Promotes the NF-κB Signaling via Decreasingly Blocking Recruitment of the IKK Complex to K63-Linked Polyubiquitin Chains.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Clone Names

  • FLJ18771

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_027354.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    AK311729, FP700111

  2. NR_027355.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate 5' exon and an alternate 3' exon, compared to variant 1.
    Source sequence(s)
    AI087158, AK311729, BE814857, BG716766, DA808118
    Related
    ENST00000690033.3

  3. NR_027356.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has alternate 5' and 3' exons and lacks an internal alternate exon, compared to variant 1.
    Source sequence(s)
    AI087158, AK311729, AW954772, DA808118
    Related
    ENST00000686318.3

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    144716079..144740806
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    143326556..143351287 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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