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ARL14EPL ADP ribosylation factor like GTPase 14 effector protein like [ Homo sapiens (human) ]

Gene ID: 644100, updated on 5-Mar-2024

Summary

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Official Symbol
ARL14EPLprovided by HGNC
Official Full Name
ADP ribosylation factor like GTPase 14 effector protein likeprovided by HGNC
Primary source
HGNC:HGNC:44201
See related
Ensembl:ENSG00000268223 AllianceGenome:HGNC:44201
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

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Location:
5q23.1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (116032472..116059489)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (116544843..116571873)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (115368169..115395186)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22940 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22941 Neighboring gene lincRNA adipogenesis and lipogenesis associated Neighboring gene DEAD-box helicase 43 pseudogene 1 Neighboring gene laeverin Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22942 Neighboring gene ribosomal protein S25 pseudogene 6 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22943 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22944 Neighboring gene Sharpr-MPRA regulatory region 6 Neighboring gene MPRA-validated peak5429 silencer Neighboring gene COMM domain containing 10 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16257 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:115527171-115527671 Neighboring gene RNA, U6 small nuclear 644, pseudogene Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene 27

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Spindle Assembly Checkpoint Inhibition Can Resensitize p53-Null Stem Cells to Cancer Chemotherapy. Liu C, et al. Cancer Res, 2019 May 1. PMID 30862715, Free PMC Article
  2. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Dias Neto E, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10737800, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
ARL14 effector protein-like
Names
ADP-ribosylation factor-like 14 effector protein-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195581.2 → NP_001182510.1  ARL14 effector protein-like isoform 1

    See identical proteins and their annotated locations for NP_001182510.1

    Status: VALIDATED

    Source sequence(s)
    AC034236
    Consensus CDS
    CCDS59490.1
    UniProtKB/Swiss-Prot
    P0DKL9
    Related
    ENSP00000510304.1, ENST00000686077.1
    Conserved Domains (1) summary
    pfam14949
    Location:36 → 138
    ARF7EP_C; ARF7 effector protein C-terminus

  2. NM_001385024.1 → NP_001371953.1  ARL14 effector protein-like isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC034236
    Conserved Domains (1) summary
    pfam14949
    Location:1 → 72
    ARF7EP_C; ARF7 effector protein C-terminus

  3. NM_001393974.1 → NP_001380903.1  ARL14 effector protein-like isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC034236
    Consensus CDS
    CCDS59490.1
    UniProtKB/Swiss-Prot
    P0DKL9
    Related
    ENSP00000472409.1, ENST00000601302.3
    Conserved Domains (1) summary
    pfam14949
    Location:36 → 138
    ARF7EP_C; ARF7 effector protein C-terminus

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    116032472..116059489
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    116544843..116571873
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0DKL9.1 GenPept UniProtKB/Swiss-Prot:P0DKL9

Gene LinkOut

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