atp1b2a ATPase Na+/K+ transporting subunit beta 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: atp1b2aprovided by ZNC
Official Full Name: ATPase Na+/K+ transporting subunit beta 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-001127-2
See related: Ensembl:ENSDARG00000099203 AllianceGenome:ZFIN:ZDB-GENE-001127-2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb711; atp1b2; zgc:86580; wu:fc09e11
Summary: Predicted to enable ATPase activator activity. Predicted to be involved in cellular monovalent inorganic cation homeostasis and inorganic cation transmembrane transport. Predicted to act upstream of or within potassium ion transport and sodium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Is expressed in nervous system; neural rod; neural tube; and pancreatic bud. Orthologous to human ATP1B2 (ATPase Na+/K+ transporting subunit beta 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (44732814..44763864)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (45020817..45050137)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATPase activator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in intracellular potassium ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular sodium ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
involved_in potassium ion import across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within potassium ion transport	IEA Inferred from Electronic Annotation more info
involved_in sodium ion export across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within sodium ion transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of sodium:potassium-exchanging ATPase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of sodium:potassium-exchanging ATPase complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ATPase, Na+/K+ transporting, beta 2a polypeptide; sodium/potassium-transporting ATPase subunit beta-2a

Names: ATPase, Na+/K+ beta 2 polypeptide; ATPase, Na+/K+ transporting, beta 2 polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131669.3 → NP_571744.1 sodium/potassium-transporting ATPase subunit beta-2a

See identical proteins and their annotated locations for NP_571744.1

Status: PROVISIONAL

Source sequence(s)

BC078647

UniProtKB/TrEMBL

A0A0R4IT77, Q6AZA3, Q9DGL2

Related

ENSDARP00000139476.1, ENSDART00000160044.2

Conserved Domains (1) summary

pfam00287
Location:8 → 278

Na_K-ATPase; Sodium / potassium ATPase beta chain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007134.7 Reference GRCz11 Primary Assembly

Range

44732814..44763864

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021469844.1 → XP_021325519.1 ATPase, Na+/K+ transporting, beta 2a polypeptide isoform X1

UniProtKB/TrEMBL

A0A8M9PKU7

Related

ENSDARP00000138154.1, ENSDART00000166421.2

Conserved Domains (1) summary

pfam00287
Location:7 → 287

Na_K-ATPase; Sodium / potassium ATPase beta chain