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efna5a ephrin-A5a [ Danio rerio (zebrafish) ]

Gene ID: 64256, updated on 2-Nov-2024

Summary

Official Symbol
efna5aprovided by ZNC
Official Full Name
ephrin-A5aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-001128-1
See related
AllianceGenome:ZFIN:ZDB-GENE-001128-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
L2; cb1080; fl02c06; wu:fl02c06
Summary
Predicted to enable ephrin receptor binding activity. Predicted to be involved in several processes, including axon guidance; ephrin receptor signaling pathway; and regulation of actin cytoskeleton organization. Predicted to act upstream of or within cell differentiation and nervous system development. Predicted to be located in side of membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including anterior neural keel; immature eye; nervous system; neural plate; and neural tube. Orthologous to human EFNA5 (ephrin A5). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See efna5a in Genome Data Viewer
Location:
chromosome: 21
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (20548698..20633384)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (20512049..20597382)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene si:dkey-30k6.5 Neighboring gene zgc:103482 Neighboring gene growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1 Neighboring gene growth arrest and DNA damage-inducible protein GADD45 gamma-like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ephrin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ephrin receptor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in ephrin receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within ephrin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    20548698..20633384
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001337352.8XP_001337388.4  ephrin-A5b isoform X1

    UniProtKB/TrEMBL
    A0A8M1PZ39
    Conserved Domains (1) summary
    cd10425
    Location:30159
    Ephrin-A_Ectodomain; Ectodomain of Ephrin A
  2. XM_005161235.5XP_005161292.1  ephrin-A5b isoform X2

    UniProtKB/TrEMBL
    A0A8M2B861
    Conserved Domains (1) summary
    cd10425
    Location:30159
    Ephrin-A_Ectodomain; Ectodomain of Ephrin A