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Defb13 defensin beta 13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 641626, updated on 2-Nov-2024

Summary

Official Symbol
Defb13provided by RGD
Official Full Name
defensin beta 13provided by RGD
Primary source
RGD:1559883
See related
EnsemblRapid:ENSRNOG00000038157 AllianceGenome:RGD:1559883
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
BD-13
Summary
Predicted to enable lipid binding activity. Predicted to be involved in defense response to bacterium and innate immune response. Predicted to be located in extracellular region. Orthologous to several human genes including DEFB107B (defensin beta 107B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 2.9), Testes (RPKM 2.2) and 2 other tissues See more
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Genomic context

See Defb13 in Genome Data Viewer
Location:
16q12.5
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (76831868..76833977, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (70129400..70131509, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (75027131..75028977, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 90 member A1A Neighboring gene family with sequence similarity 90, member A1 like 4 Neighboring gene defensin beta 105A Neighboring gene defensin beta 15

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables lipid binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037503.2NP_001032592.1  beta-defensin 13 precursor

    See identical proteins and their annotated locations for NP_001032592.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016
    UniProtKB/Swiss-Prot
    Q32ZH8
    UniProtKB/TrEMBL
    A6IW93
    Related
    ENSRNOP00000054879.1, ENSRNOT00000058071.3

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    76831868..76833977 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)