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Ndufs6b NADH:ubiquinone oxidoreductase subunit S6B [ Mus musculus (house mouse) ]

Gene ID: 623286, updated on 2-Nov-2024

Summary

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Official Symbol
Ndufs6bprovided by MGI
Official Full Name
NADH:ubiquinone oxidoreductase subunit S6Bprovided by MGI
Primary source
MGI:MGI:3648526
See related
AllianceGenome:MGI:3648526
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm6415; EG623286
Summary
Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in cervical cancer and nuclear type mitochondrial complex I deficiency 9. Orthologous to human NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Ndufs6b in Genome Data Viewer
Location:
7 D3; 7 45.71 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (80811021..80811494, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (81161273..81161746, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 592 Neighboring gene STARR-seq mESC enhancer starr_19350 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:88220222-88220409 Neighboring gene alpha-kinase 3 Neighboring gene predicted gene, 51490 Neighboring gene solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 Neighboring gene STARR-seq mESC enhancer starr_19353 Neighboring gene STARR-positive B cell enhancer mm9_chr7:88299922-88300223 Neighboring gene STARR-seq mESC enhancer starr_19358 Neighboring gene predicted gene 44968 Neighboring gene phosphodiesterase 8A Neighboring gene translocase of inner mitochondrial membrane 17a pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
part_of respiratory chain complex I ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial-like
Names
predicted pseudogene 6415

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    80811021..80811494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153659.1 → XP_036009552.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial-like

    UniProtKB/TrEMBL
    A0A1Y7VM38
    Conserved Domains (2) summary
    PRK08235
    Location:54 → 89
    PRK08235; acetyl-CoA C-acetyltransferase
    pfam10276
    Location:75 → 111
    zf-CHCC; Zinc-finger domain
Nucleotide Protein Strain
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