LDB2 LIM domain binding 2 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: LDB2provided by VGNC
Official Full Name: LIM domain binding 2provided by VGNC
Primary source: VGNC:VGNC:30822
See related: Ensembl:ENSBTAG00000014058
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	6	NC_037333.1 (111698867..112153622, complement)

Chromosome 6 - NC_037333.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

MARC_11947-11948:1003496306:1 (e-PCR)
- UniSTS:267289

D11S3498 (e-PCR)
- UniSTS:152737

LDB2 (e-PCR)
- UniSTS:519164

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables LIM domain binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nervous system development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
part_of transcription regulator complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: LIM domain-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001046611.3 → NP_001040076.2 LIM domain-binding protein 2 isoform 2

See identical proteins and their annotated locations for NP_001040076.2

Status: VALIDATED

Description

Transcript Variant: This variant (2) uses an alternate in-frame splice site in its 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.

Source sequence(s)

EE228807, EV635520, EV700765, NKLS02000006

UniProtKB/TrEMBL

Q2KJI8

Conserved Domains (1) summary

pfam01803
Location:31 → 232

LIM_bind; LIM-domain binding protein
NM_001314058.1 → NP_001300987.1 LIM domain-binding protein 2 isoform 1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

Source sequence(s)

EE228807, EV635520, EV700765, NKLS02000006

UniProtKB/TrEMBL

A0AAA9S778, Q2KJI8

Related

ENSBTAP00000081066.1, ENSBTAT00000113125.1

Conserved Domains (1) summary

pfam01803
Location:31 → 232

LIM_bind; LIM-domain binding protein

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

Range

111698867..112153622 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024993437.2 → XP_024849205.1 LIM domain-binding protein 2 isoform X5

UniProtKB/TrEMBL

A0AAA9SX04

Conserved Domains (1) summary

pfam01803
Location:31 → 232

LIM_bind; LIM-domain binding protein
XM_015471777.2 → XP_015327263.1 LIM domain-binding protein 2 isoform X4

UniProtKB/TrEMBL

A0AAA9SX04

Conserved Domains (1) summary

pfam01803
Location:31 → 232

LIM_bind; LIM-domain binding protein
XM_015471776.3 → XP_015327262.1 LIM domain-binding protein 2 isoform X3

UniProtKB/TrEMBL

A0AAA9SX04

Related

ENSBTAP00000088781.1, ENSBTAT00000112621.1

Conserved Domains (1) summary

pfam01803
Location:31 → 232

LIM_bind; LIM-domain binding protein
XM_005208318.4 → XP_005208375.1 LIM domain-binding protein 2 isoform X2

See identical proteins and their annotated locations for XP_005208375.1

UniProtKB/TrEMBL

Q2KJI8

Conserved Domains (1) summary

pfam01803
Location:31 → 232

LIM_bind; LIM-domain binding protein
XM_005208317.3 → XP_005208374.1 LIM domain-binding protein 2 isoform X1

See identical proteins and their annotated locations for XP_005208374.1

UniProtKB/TrEMBL

Q2KJI8

Conserved Domains (1) summary

pfam01803
Location:31 → 232

LIM_bind; LIM-domain binding protein
XM_005208320.5 → XP_005208377.1 LIM domain-binding protein 2 isoform X6

UniProtKB/TrEMBL

A0AAA9SX04, F6R129

Related

ENSBTAP00000018687.6, ENSBTAT00000018687.6

Conserved Domains (1) summary

pfam01803
Location:31 → 232

LIM_bind; LIM-domain binding protein