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ISL1 ISL LIM homeobox 1 [ Bos taurus (domestic cattle) ]

Gene ID: 614040, updated on 10-Oct-2024

Summary

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Official Symbol
ISL1provided by VGNC
Official Full Name
ISL LIM homeobox 1provided by VGNC
Primary source
VGNC:VGNC:30296
See related
BGD:BT28276; Ensembl:ENSBTAG00000001241
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
islet-1
Orthologs
human mouse all
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Genomic context

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See ISL1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 20 NC_037347.1 (27683360..27744047, complement)

Chromosome 20 - NC_037347.1Genomic Context describing neighboring genes Neighboring gene integrin subunit alpha 1 Neighboring gene pelota mRNA surveillance and ribosome rescue factor Neighboring gene uncharacterized LOC132343185 Neighboring gene uncharacterized LOC132343225 Neighboring gene uncharacterized LOC132343224 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037347.1 Chromosome 20 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC166050

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron fate specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin gene enhancer protein ISL-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099130.1 → NP_001092600.1  insulin gene enhancer protein ISL-1

    See identical proteins and their annotated locations for NP_001092600.1

    Status: PROVISIONAL

    Source sequence(s)
    BC146163
    UniProtKB/TrEMBL
    A0AAA9TU30, A6H796, F1MI36
    Related
    ENSBTAP00000093494.1, ENSBTAT00000104342.1
    Conserved Domains (3) summary
    cd09366
    Location:17 → 71
    LIM1_Isl; The first LIM domain of Isl, a member of LHX protein family
    cd09374
    Location:79 → 133
    LIM2_Isl; The second LIM domain of Isl, a member of LHX protein family
    smart00389
    Location:181 → 237
    HOX; Homeodomain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037347.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    27683360..27744047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059878787.1 → XP_059734770.1  insulin gene enhancer protein ISL-1 isoform X1

    Related
    ENSBTAP00000001638.5, ENSBTAT00000001638.6
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials