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lepA translation elongation factor 4 [ Brucella anthropi ]

Gene ID: 61318156, updated on 8-Aug-2024

Summary

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Gene symbol
lepA
Gene description
translation elongation factor 4
Locus tag
IR196_RS19310
Gene type
protein coding
Organism
Brucella anthropi (strain: PBO)
Lineage
Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales; Brucellaceae; Brucella/Ochrobactrum group; Brucella
Old locus tag
IR196_19310
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Genomic context

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Location:
chromosome: 2

2 - NZ_CP064063.1Genomic Context describing neighboring genes Neighboring gene SelT/SelW/SelH family protein Neighboring gene GIY-YIG nuclease family protein Neighboring gene complex I NDUFA9 subunit family protein Neighboring gene undecaprenyl-diphosphate phosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP064063.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Complete Genome Assembly of Reference Strain Ochrobactrum anthropi ATCC 49687. Minogue TD, et al. Genome Announc, 2014 Sep 25. PMID 25291772, Free PMC Article
  2. EF4 reveals the energy barrier for tRNA back-translocation in the peptidyl transferase center. Song G, et al. RNA Biol, 2016 Oct 2. PMID 27472653, Free PMC Article
  3. The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis. Liu H, et al. Proc Natl Acad Sci U S A, 2011 Sep 27. PMID 21930951, Free PMC Article
  4. Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome. Gibbs MR, et al. Proc Natl Acad Sci U S A, 2017 Jan 31. PMID 28096346, Free PMC Article
  5. Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome. Kumar V, et al. J Biol Chem, 2016 Jun 17. PMID 27137929, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
translation elongation factor 4
WP_010659407.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP064063.1 Reference assembly

    Range
    2023303..2025111 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010659407.1 MULTISPECIES: translation elongation factor 4 [Brucella/Ochrobactrum group]

    See identical proteins and their annotated locations for WP_010659407.1

    UniProtKB/Swiss-Prot
    A6WYK4
    UniProtKB/TrEMBL
    A0A011TA76, A0A1J6I170, A0A256GWV7
    Conserved Domains (1) summary
    PRK05433
    Location:2 → 602
    PRK05433; GTP-binding protein LepA; Provisional
Nucleotide Protein
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