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GAD1 glutamate decarboxylase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 613030, updated on 17-Aug-2024

Summary

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Official Symbol
GAD1provided by VGNC
Official Full Name
glutamate decarboxylase 1provided by VGNC
Primary source
VGNC:VGNC:72862
Locus tag
EGK_04525
See related
Ensembl:ENSMMUG00000015198
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
GAD67
Orthologs
human mouse all
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Genomic context

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See GAD1 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (57960027..58006388)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (57856065..57902253)

Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114671350 Neighboring gene glutamate rich 2 Neighboring gene uncharacterized LOC114671352 Neighboring gene golgi reassembly stacking protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of glutamic acid decarboxylase in the prepubertal inhibition of the luteinizing hormone releasing hormone release in female rhesus monkeys. Mitsushima D, et al. J Neurosci, 1996 Apr 15. PMID 8786432, Free PMC Article
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glutamate decarboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in gamma-aminobutyric acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynaptic active zone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glutamate decarboxylase 1
Names
67kDa glutamate decarboxylase 1
glutamate decarboxylase 1 (brain, 67kDa)
glutamic acid decarboxylase
XP_014965837.1
XP_028686664.1
XP_028686665.1
XP_028686666.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041765.1 Reference Mmul_10 Primary Assembly

    Range
    57960027..58006388
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015110351.2 → XP_014965837.1  glutamate decarboxylase 1 isoform X1

    UniProtKB/TrEMBL
    A0A663D8I6, A0A8J8YFI2, F6W3Q6, F6W3S5, F7GMA1, G7N8A4
    Related
    ENSMMUP00000019935.3, ENSMMUT00000021316.4
    Conserved Domains (1) summary
    pfam00282
    Location:144 → 518
    Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

  2. XM_028830832.1 → XP_028686665.1  glutamate decarboxylase 1 isoform X2

    Conserved Domains (1) summary
    cl18945
    Location:144 → 213
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

  3. XM_028830833.1 → XP_028686666.1  glutamate decarboxylase 1 isoform X2

    Conserved Domains (1) summary
    cl18945
    Location:144 → 213
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

  4. XM_028830831.1 → XP_028686664.1  glutamate decarboxylase 1 isoform X1

    UniProtKB/TrEMBL
    A0A663D8I6, A0A8J8YFI2, F6W3Q6, F6W3S5, F7GMA1, G7N8A4
    Related
    ENSMMUP00000019936.4, ENSMMUT00000021317.4
    Conserved Domains (1) summary
    pfam00282
    Location:144 → 518
    Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain
Nucleotide Protein
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