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GFRA2 GDNF family receptor alpha 2 [ Canis lupus familiaris (dog) ]

Gene ID: 609172, updated on 17-Aug-2024

Summary

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Official Symbol
GFRA2provided by VGNC
Official Full Name
GDNF family receptor alpha 2provided by VGNC
Primary source
VGNC:VGNC:41190
See related
Ensembl:ENSCAFG00845028779
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See GFRA2 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (35653939..35732615)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (36025500..36109252)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (35603029..35686767)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (35593224..35677046)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (35447108..35531948)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111092483 Neighboring gene exportin 7 Neighboring gene uncharacterized LOC119865951 Neighboring gene docking protein 2 Neighboring gene putative elongation factor 1-alpha-like 3 Neighboring gene uncharacterized LOC111092460

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GDNF family receptor alpha-2; LOW QUALITY PROTEIN: GDNF family receptor alpha-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    35653939..35732615
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038435519.1 → XP_038291447.1  LOW QUALITY PROTEIN: GDNF family receptor alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PG82, A0A8P0TLN5
    Related
    ENSCAFP00845040058.1, ENSCAFT00845051091.1
    Conserved Domains (2) summary
    smart00907
    Location:36 → 109
    GDNF; GDNF/GAS1 domain
    pfam02351
    Location:247 → 343
    GDNF; GDNF/GAS1 domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    35593224..35677046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038510463.1 → XP_038366391.1  GDNF family receptor alpha-2 isoform X2

    Conserved Domains (2) summary
    smart00907
    Location:40 → 113
    GDNF; GDNF/GAS1 domain
    pfam02351
    Location:251 → 347
    GDNF; GDNF/GAS1 domain

  2. XM_038510462.1 → XP_038366390.1  GDNF family receptor alpha-2 isoform X2

    Conserved Domains (2) summary
    smart00907
    Location:40 → 113
    GDNF; GDNF/GAS1 domain
    pfam02351
    Location:251 → 347
    GDNF; GDNF/GAS1 domain

  3. XM_038510461.1 → XP_038366389.1  GDNF family receptor alpha-2 isoform X2

    Conserved Domains (2) summary
    smart00907
    Location:40 → 113
    GDNF; GDNF/GAS1 domain
    pfam02351
    Location:251 → 347
    GDNF; GDNF/GAS1 domain

  4. XM_038510464.1 → XP_038366392.1  GDNF family receptor alpha-2 isoform X3

    Conserved Domains (1) summary
    pfam02351
    Location:180 → 276
    GDNF; GDNF/GAS1 domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    35447108..35531948
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038638228.1 → XP_038494156.1  GDNF family receptor alpha-2 isoform X4

    Conserved Domains (2) summary
    smart00907
    Location:40 → 113
    GDNF; GDNF/GAS1 domain
    pfam02351
    Location:251 → 347
    GDNF; GDNF/GAS1 domain

  2. XM_038638227.1 → XP_038494155.1  GDNF family receptor alpha-2 isoform X4

    Conserved Domains (2) summary
    smart00907
    Location:40 → 113
    GDNF; GDNF/GAS1 domain
    pfam02351
    Location:251 → 347
    GDNF; GDNF/GAS1 domain

  3. XM_038638229.1 → XP_038494157.1  GDNF family receptor alpha-2 isoform X5

    Conserved Domains (1) summary
    pfam02351
    Location:180 → 276
    GDNF; GDNF/GAS1 domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    35603029..35686767
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038573910.1 → XP_038429838.1  GDNF family receptor alpha-2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0L156, A0A8C0PG59, A0A8C0PG82, A0A8I3Q4U8, A0A8P0TLN5
    Conserved Domains (2) summary
    smart00907
    Location:40 → 113
    GDNF; GDNF/GAS1 domain
    pfam02351
    Location:251 → 347
    GDNF; GDNF/GAS1 domain

  2. XM_038573909.1 → XP_038429837.1  GDNF family receptor alpha-2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0L156, A0A8C0PG59, A0A8C0PG82, A0A8I3Q4U8, A0A8P0TLN5
    Conserved Domains (2) summary
    smart00907
    Location:40 → 113
    GDNF; GDNF/GAS1 domain
    pfam02351
    Location:251 → 347
    GDNF; GDNF/GAS1 domain

  3. XM_038573911.1 → XP_038429839.1  GDNF family receptor alpha-2 isoform X7

    UniProtKB/TrEMBL
    A0A8C0PG82, A0A8P0TLN5
    Conserved Domains (1) summary
    pfam02351
    Location:180 → 276
    GDNF; GDNF/GAS1 domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    36025500..36109252
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014107598.3 → XP_013963073.2  GDNF family receptor alpha-2 isoform X8

    UniProtKB/TrEMBL
    A0A8C0L156, A0A8C0PG59, A0A8C0PG82, A0A8I3Q4U8, A0A8P0TLN5
    Conserved Domains (2) summary
    smart00907
    Location:40 → 113
    GDNF; GDNF/GAS1 domain
    pfam02351
    Location:251 → 347
    GDNF; GDNF/GAS1 domain

  2. XM_038458696.1 → XP_038314624.1  GDNF family receptor alpha-2 isoform X8

    UniProtKB/TrEMBL
    A0A8C0L156, A0A8C0PG59, A0A8C0PG82, A0A8I3Q4U8, A0A8P0TLN5
    Conserved Domains (2) summary
    smart00907
    Location:40 → 113
    GDNF; GDNF/GAS1 domain
    pfam02351
    Location:251 → 347
    GDNF; GDNF/GAS1 domain

  3. XM_038458697.1 → XP_038314625.1  GDNF family receptor alpha-2 isoform X9

    UniProtKB/TrEMBL
    A0A8C0PG82, A0A8P0TLN5
    Conserved Domains (1) summary
    pfam02351
    Location:180 → 276
    GDNF; GDNF/GAS1 domain
Nucleotide Protein
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