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LRRC4 leucine rich repeat containing 4 [ Canis lupus familiaris (dog) ]

Gene ID: 607997, updated on 17-Aug-2024

Summary

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Official Symbol
LRRC4provided by VGNC
Official Full Name
leucine rich repeat containing 4provided by VGNC
Primary source
VGNC:VGNC:42797
See related
Ensembl:ENSCAFG00845025632
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See LRRC4 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
2
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (8090773..8094337)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (8010280..8013846)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (8182826..8186395)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (8295211..8298775)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (8035990..8039549)

Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866729 Neighboring gene uncharacterized LOC119866555 Neighboring gene uncharacterized LOC111098732 Neighboring gene staphylococcal nuclease and tudor domain containing 1 Neighboring gene 40S ribosomal protein S8-like Neighboring gene complex III assembly factor LYRM7-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in excitatory synapse assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in modulation of chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in postsynaptic density protein 95 clustering IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic membrane adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leucine-rich repeat-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051818.1 Reference ROS_Cfam_1.0

    Range
    8090773..8094337
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038686229.1 → XP_038542157.1  leucine-rich repeat-containing protein 4

    UniProtKB/TrEMBL
    A0A8C0LAK3, A0A8C0MTE6, A0A8I3PVC0, A0A8P0PMQ4
    Related
    ENSCAFP00845035471.1, ENSCAFT00845045237.1
    Conserved Domains (7) summary
    smart00013
    Location:45 → 78
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:299 → 350
    LRRCT; Leucine rich repeat C-terminal domain
    smart00410
    Location:358 → 440
    IG_like; Immunoglobulin like
    COG4886
    Location:73 → 290
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:76 → 99
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:74 → 132
    LRR_8; Leucine rich repeat
    cd00096
    Location:352 → 355
    Ig; Ig strand A [structural motif]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049274.1 Alternate UMICH_Zoey_3.1

    Range
    8295211..8298775
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038494314.1 → XP_038350242.1  leucine-rich repeat-containing protein 4

    Conserved Domains (7) summary
    smart00013
    Location:45 → 78
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:299 → 350
    LRRCT; Leucine rich repeat C-terminal domain
    smart00410
    Location:358 → 440
    IG_like; Immunoglobulin like
    COG4886
    Location:73 → 290
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:76 → 99
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:74 → 132
    LRR_8; Leucine rich repeat
    cd00096
    Location:352 → 355
    Ig; Ig strand A [structural motif]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

    Range
    8035990..8039549
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038620540.1 → XP_038476468.1  leucine-rich repeat-containing protein 4

    Conserved Domains (7) summary
    smart00013
    Location:45 → 78
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:299 → 350
    LRRCT; Leucine rich repeat C-terminal domain
    smart00410
    Location:358 → 440
    IG_like; Immunoglobulin like
    COG4886
    Location:73 → 290
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:76 → 99
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:74 → 132
    LRR_8; Leucine rich repeat
    cd00096
    Location:352 → 355
    Ig; Ig strand A [structural motif]

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

    Range
    8182826..8186395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038556611.1 → XP_038412539.1  leucine-rich repeat-containing protein 4

    UniProtKB/TrEMBL
    A0A8C0LAK3, A0A8C0MTE6, A0A8I3PVC0, A0A8P0PMQ4
    Conserved Domains (7) summary
    smart00013
    Location:45 → 78
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:299 → 350
    LRRCT; Leucine rich repeat C-terminal domain
    smart00410
    Location:358 → 440
    IG_like; Immunoglobulin like
    COG4886
    Location:73 → 290
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:76 → 99
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:74 → 132
    LRR_8; Leucine rich repeat
    cd00096
    Location:352 → 355
    Ig; Ig strand A [structural motif]

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8010280..8013846
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_844368.6 → XP_849461.1  leucine-rich repeat-containing protein 4

    See identical proteins and their annotated locations for XP_849461.1

    UniProtKB/TrEMBL
    A0A8C0LAK3, A0A8C0MTE6, A0A8I3PVC0, A0A8P0PMQ4
    Conserved Domains (7) summary
    smart00013
    Location:45 → 78
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:299 → 350
    LRRCT; Leucine rich repeat C-terminal domain
    smart00410
    Location:358 → 440
    IG_like; Immunoglobulin like
    COG4886
    Location:73 → 290
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:76 → 99
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:74 → 132
    LRR_8; Leucine rich repeat
    cd00096
    Location:352 → 355
    Ig; Ig strand A [structural motif]
Nucleotide Protein
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