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spxA transcriptional regulator Spx [ Streptococcus pneumoniae Hungary19A-6 ]

Gene ID: 6028201, discontinued on 6-Feb-2015
  • All Gene records for this genome have been discontinued due to a change in scope for prokaryotic genomes in Gene. At the time this Gene record was discontinued, the RefSeq genome was re-annotated with the following features at this location:

Summary

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Gene symbol
spxA
Gene description
transcriptional regulator Spx
Locus tag
SPH_1536
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Streptococcus pneumoniae Hungary19A-6 (strain: Hungary19A-6)
Lineage
Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
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Genomic regions, transcripts, and products

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Genomic Sequence:
NC_010380.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General protein information

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Names
transcriptional regulator Spx
YP_001694840.1
  • the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_010380.1 Reference assembly

    Range
    1422333..1422734 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_001694840.1 transcriptional regulator Spx [Streptococcus pneumoniae Hungary19A-6]

    Status: PROVISIONAL

Nucleotide Protein
Heading Accession and Version