alg2 ALG2, alpha-1,3/1,6-mannosyltransferase [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: alg2provided by Xenbase
Official Full Name: ALG2, alpha-1,3/1,6-mannosyltransferaseprovided by Xenbase
Primary source: Xenbase:XB-GENE-494529
See related: Ensembl:ENSXETG00000011972
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: cdgii; halpg2
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	6	NC_030682.2 (64969249..64974252)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	6	NC_030682.1 (82176000..82180995)

Chromosome 6 - NC_030682.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: alpha-1,3/1,6-mannosyltransferase ALG2

Names: asparagine-linked glycosylation 2 homolog

NP_001025660.1

EC 2.4.1.132

EC 2.4.1.257

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001030489.1 → NP_001025660.1 alpha-1,3/1,6-mannosyltransferase ALG2

See identical proteins and their annotated locations for NP_001025660.1

Status: PROVISIONAL

Source sequence(s)

BC092211

UniProtKB/TrEMBL

A0A803KL01, F6Y018, Q56A17

Related

ENSXETP00000026182.4, ENSXETT00000026182.5

Conserved Domains (1) summary

cd03805
Location:4 → 395

GT1_ALG2_like; This family is most closely related to the GT1 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2) ...