aph1a.S aph-1 homolog A, gamma secretase subunit S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: aph1a.S
Official Full Name: aph-1 homolog A, gamma secretase subunit S homeolog
Primary source: Xenbase:XB-GENE-921439
Locus tag: XELAEV_18042790mg
See related: EnsemblRapid:ENSXLAG00005022834
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: aph1a
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Genomic context

Location:: chromosome: 8S

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8S	NC_054386.1 (98597601..98608715, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8S	NC_030739.1 (93555719..93567109, complement)

Chromosome 8S - NC_054386.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables protein-macromolecule adaptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within Notch receptor processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within Notch signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of catalytic activity	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
part_of gamma-secretase complex	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: aph-1 homolog A, gamma secretase subunit S homeolog

Names: APH1A gamma secretase subunit; anterior pharynx defective 1 homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001095587.1 → NP_001089056.1 aph-1 homolog A, gamma secretase subunit S homeolog

See identical proteins and their annotated locations for NP_001089056.1

Status: PROVISIONAL

Source sequence(s)

BC089044

UniProtKB/TrEMBL

A0A974C5Z9, Q5HZF9

Related

ENSXLAP00005067214.1, ENSXLAT00005068742.1

Conserved Domains (1) summary

pfam06105
Location:3 → 233

Aph-1; Aph-1 protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

98597601..98608715 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)