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b3gat3 beta-1,3-glucuronyltransferase 3 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 594895, updated on 4-Nov-2024

Summary

Official Symbol
b3gat3provided by Xenbase
Official Full Name
beta-1,3-glucuronyltransferase 3provided by Xenbase
Primary source
Xenbase:XB-GENE-1010243
See related
Ensembl:ENSXETG00000005581 AllianceGenome:Xenbase:XB-GENE-1010243
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
glcati
Summary
Predicted to enable galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity and metal ion binding activity. Predicted to act upstream of or within protein glycosylation. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in Larsen-like syndrome B3GAT3 type. Orthologous to human B3GAT3 (beta-1,3-glucuronyltransferase 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See b3gat3 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
7
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (36910365..36919471, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (41607515..41618367, complement)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene echinoderm microtubule associated protein like 3 Neighboring gene retinal outer segment membrane protein 1 Neighboring gene glucosidase, alpha; neutral AB Neighboring gene small nucleolar RNA SNORD31

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC144949

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
Names
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
beta-3-glucuronyltransferase-I
NP_001025520.1
XP_012809781.2
XP_012809782.2
XP_012809783.2
XP_012809784.2
XP_012809785.2
XP_031755981.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030349.1NP_001025520.1  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

    See identical proteins and their annotated locations for NP_001025520.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ890837
    UniProtKB/TrEMBL
    Q0VA80, Q599K4
    Conserved Domains (1) summary
    cd00218
    Location:53281
    GlcAT-I; Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    36910365..36919471 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012954331.3XP_012809785.2  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform X1

    UniProtKB/TrEMBL
    F6WKR0, Q0VA80
    Conserved Domains (1) summary
    cd00218
    Location:60288
    GlcAT-I; Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis
  2. XM_012954330.3XP_012809784.2  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform X1

    UniProtKB/TrEMBL
    F6WKR0, Q0VA80
    Conserved Domains (1) summary
    cd00218
    Location:60288
    GlcAT-I; Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis
  3. XM_031900121.1XP_031755981.1  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform X1

    UniProtKB/TrEMBL
    F6WKR0, Q0VA80
    Related
    ENSXETP00000103597.1, ENSXETT00000112865.1
    Conserved Domains (1) summary
    cd00218
    Location:60288
    GlcAT-I; Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis
  4. XM_012954329.3XP_012809783.2  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform X1

    UniProtKB/TrEMBL
    F6WKR0, Q0VA80
    Conserved Domains (1) summary
    cd00218
    Location:60288
    GlcAT-I; Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis
  5. XM_012954328.3XP_012809782.2  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform X1

    UniProtKB/TrEMBL
    F6WKR0, Q0VA80
    Related
    ENSXETP00000115135.1, ENSXETT00000119215.1
    Conserved Domains (1) summary
    cd00218
    Location:60288
    GlcAT-I; Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis
  6. XM_012954327.3XP_012809781.2  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 isoform X1

    UniProtKB/TrEMBL
    F6WKR0, Q0VA80
    Related
    ENSXETP00000012291.4, ENSXETT00000012291.5
    Conserved Domains (1) summary
    cd00218
    Location:60288
    GlcAT-I; Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis