tcea1.L transcription elongation factor A (SII), 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: tcea1.L
Official Full Name: transcription elongation factor A (SII), 1 L homeolog
Primary source: Xenbase:XB-GENE-1001321
Locus tag: XELAEV_18032014mg
See related: EnsemblRapid:ENSXLAG00005016217 AllianceGenome:Xenbase:XB-GENE-1001321
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: sii; tcea; tf2s; TFIIS; gtf2s; tcea1; x-tfIIs
Summary: Predicted to enable DNA binding activity; translation elongation factor activity; and zinc ion binding activity. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II; transcription elongation by RNA polymerase II; and translational elongation. Predicted to be located in nucleus. Is expressed in anatomical system and pharyngeal arch. Orthologous to human TCEA1 (transcription elongation factor A1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 6L

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	6L	NC_054381.1 (122666635..122682111, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	6L	NC_030734.1 (115541679..115557157, complement)

Chromosome 6L - NC_054381.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables translation elongation factor activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within transcription elongation by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translational elongation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: transcription elongation factor A (SII), 1 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001095577.1 → NP_001089046.1 transcription elongation factor A (SII), 1 L homeolog

See identical proteins and their annotated locations for NP_001089046.1

Status: PROVISIONAL

Source sequence(s)

BC070555

UniProtKB/TrEMBL

A0A974CR04, Q91980

Related

ENSXLAP00005047720.1, ENSXLAT00005048835.1

Conserved Domains (4) summary

cd00183
Location:5 → 81

TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme

cd13749
Location:256 → 302

Zn-ribbon_TFIIS; domain III/zinc ribbon domain of Transcription Factor IIS

TIGR01385
Location:5 → 303

TFSII; transcription elongation factor S-II

pfam07500
Location:140 → 247

TFIIS_M; Transcription factor S-II (TFIIS), central domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

122666635..122682111 complement

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GenBank, FASTA, Sequence Viewer (Graphics)