cdh3.L cadherin 3 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: cdh3.L
Official Full Name: cadherin 3 L homeolog
Primary source: Xenbase:XB-GENE-864850
Locus tag: XELAEV_18022638mg
See related: EnsemblRapid:ENSXLAG00005028667 AllianceGenome:Xenbase:XB-GENE-864850
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: uvo; cdh1; cdh3; cdhp; hjmd; lcam; pcad; E-Cad; l-cam; xcdh1; cdh1-b; cdh3-a; cdh3-b; cdhc-A; xb-cad; XTCAD-1; E-cadherin; P-cadherin; U-cadherin; c-cadherin; cadherin-1; uvomorulin; EP-cadherin
Summary: Predicted to enable cadherin binding activity and calcium ion binding activity. Predicted to act upstream of or within several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; and cell-cell junction organization. Predicted to be located in adherens junction; cytoplasm; and plasma membrane. Predicted to be part of catenin complex. Is expressed in ectoderm and endoderm. Human ortholog(s) of this gene implicated in congenital hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome. Orthologous to human CDH3 (cadherin 3). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4L	NC_054377.1 (55350923..55385139, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4L	NC_030730.1 (50138834..50173094, complement)

Chromosome 4L - NC_054377.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables cadherin binding	IEA Inferred from Electronic Annotation more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within adherens junction organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell morphogenesis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell-cell adhesion mediated by cadherin	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell-cell junction assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within homophilic cell adhesion via plasma membrane adhesion molecules	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in adherens junction	IEA Inferred from Electronic Annotation more info
part_of catenin complex	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

Names: B-cadherin; Blastomere cadherin; XB-cadherin; XBcad; cadherin 1, type 1, E-cadherin (epithelial); cadherin 3, type 1, P-cadherin (placental) L homeolog

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain

The following Reference Sequences have been suppressed. Explain

NM_001095576.1: Suppressed sequence

Description

NM_001095576.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.