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fgd faciogenital dysplasia [ Danio rerio (zebrafish) ]

Gene ID: 58075, updated on 2-Nov-2024

Summary

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Official Symbol
fgdprovided by ZNC
Official Full Name
faciogenital dysplasiaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-000517-1
See related
AllianceGenome:ZFIN:ZDB-GENE-000517-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable guanyl-nucleotide exchange factor activity and metal ion binding activity. Predicted to be located in cytoplasm and cytoskeleton. Is expressed in cornea. [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
Orthologs
all
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Genomic context

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See fgd in Genome Data Viewer
Location:
chromosome: 8
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (53997374..54025855)
105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_008805357.1 (732..12628, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene si:ch73-236j9.2 Neighboring gene solute carrier family 35 member E2B Neighboring gene sushi domain-containing protein 3 Neighboring gene serine/threonine-protein kinase WNK2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. fgf17b, a novel member of Fgf family, helps patterning zebrafish embryos. Cao Y, et al. Dev Biol, 2004 Jul 1. PMID 15196956
  2. Molecular description of eye defects in the zebrafish Pax6b mutant, sunrise, reveals a Pax6b-dependent genetic network in the developing anterior chamber. Takamiya M, et al. PLoS One, 2015. PMID 25692557, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
faciogenital dysplasia

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131556.2 → NP_571631.2  faciogenital dysplasia

    See identical proteins and their annotated locations for NP_571631.2

    Status: PROVISIONAL

    Source sequence(s)
    BC096859
    UniProtKB/TrEMBL
    Q4V9K2
    Conserved Domains (4) summary
    cd13387
    Location:376 → 483
    PH1_FGD3; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia protein 3, N-terminal Pleckstrin homology (PH) domain
    pfam00169
    Location:376 → 469
    PH; PH domain
    pfam00621
    Location:166 → 345
    RhoGEF; RhoGEF domain
    cl22851
    Location:526 → 575
    PHD_SF; PHD finger superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    53997374..54025855
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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