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smx5 smx5 [ Danio rerio (zebrafish) ]

Gene ID: 57924, updated on 2-Nov-2024

Summary

Official Symbol
smx5provided by ZNC
Official Full Name
smx5provided by ZNC
Primary source
ZFIN:ZDB-GENE-000616-10
See related
Ensembl:ENSDARG00000103066 AllianceGenome:ZFIN:ZDB-GENE-000616-10
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
lsm2; wu:fe48h10; zgc:101795
Summary
Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of Lsm1-7-Pat1 complex and nucleus. Predicted to be active in P-body. Orthologous to human LSM2 (LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See smx5 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (28205600..28208380)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (28215039..28217819)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 17 Neighboring gene inositol polyphosphate-5-phosphatase D Neighboring gene si:ch73-14h10.2 Neighboring gene BCL6A transcription repressor a Neighboring gene transfer RNA phenylalanine (anticodon GAA)

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
contributes_to RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of Lsm1-7-Pat1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U4/U6 x U5 tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U6 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
smx5
Names
lsm2 homolog, U6 small nuclear RNA associated

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131496.2NP_571571.1  smx5

    See identical proteins and their annotated locations for NP_571571.1

    Status: VALIDATED

    Source sequence(s)
    EH449634, FP101882
    UniProtKB/TrEMBL
    A7MCE6, Q5RKP8
    Related
    ENSDARP00000156037.1, ENSDART00000190509.1
    Conserved Domains (1) summary
    cd01725
    Location:290
    LSm2; Like-Sm protein 2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    28205600..28208380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394645.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    162804..165366
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395255.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    168095..170875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_3

Genomic

  1. NW_018395378.1 Reference GRCz11 ALT_DRER_TU_3

    Range
    164756..167540
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)