nppc natriuretic peptide C [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nppcprovided by ZNC
Official Full Name: natriuretic peptide Cprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070705-24
See related: Ensembl:ENSDARG00000068126 AllianceGenome:ZFIN:ZDB-GENE-070705-24
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cnp4; si:ch211-126j24.3
Summary: Predicted to enable hormone activity and hormone receptor binding activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be located in extracellular region. Is expressed in oocyte; oocyte stage V; and ovarian follicle. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human NPPC (natriuretic peptide C). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 22

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (38614887..38621438, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (38628601..38635152, complement)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

G45034 (e-PCR)
- UniSTS:105836

G47488 (e-PCR)
- UniSTS:108264

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hormone activity	IBA Inferred from Biological aspect of Ancestor more info
enables hormone activity	IEA Inferred from Electronic Annotation more info
enables hormone receptor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within blood vessel diameter maintenance	IEA Inferred from Electronic Annotation more info
involved_in cGMP biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in receptor guanylyl cyclase signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: C-type natriuretic peptide

Names: C-type natriuretic peptide-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109940.1 → NP_001103410.1 C-type natriuretic peptide precursor

Status: PROVISIONAL

Source sequence(s)

BX088728

UniProtKB/TrEMBL

A0A8M1NEI0, A8E7F8

Related

ENSDARP00000089102.4, ENSDART00000098330.5

Conserved Domains (1) summary

pfam00212
Location:86 → 119

ANP; Atrial natriuretic peptide