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isy1 ISY1 splicing factor homolog [ Danio rerio (zebrafish) ]

Gene ID: 570205, updated on 2-Nov-2024

Summary

Official Symbol
isy1provided by ZNC
Official Full Name
ISY1 splicing factor homologprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5864
See related
Ensembl:ENSDARG00000063466 AllianceGenome:ZFIN:ZDB-GENE-030131-5864
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7159238; wu:fc23h01; wu:fi21h07; zgc:136785
Summary
Predicted to be involved in generation of catalytic spliceosome for second transesterification step and mRNA 3'-splice site recognition. Predicted to be located in nucleus. Predicted to be part of Prp19 complex and spliceosomal complex. Orthologous to several human genes including ISY1 (ISY1 splicing factor homolog). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See isy1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (474433..486532, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (447941..459808, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene RAB43, member RAS oncogene family Neighboring gene zgc:77375 Neighboring gene CCHC-type zinc finger, nucleic acid binding protein b Neighboring gene Raf-1 proto-oncogene, serine/threonine kinase b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC136785

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
part_of Prp19 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of post-mRNA release spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of post-spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
pre-mRNA-splicing factor ISY1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083563.2NP_001077032.1  pre-mRNA-splicing factor ISY1 homolog

    See identical proteins and their annotated locations for NP_001077032.1

    Status: VALIDATED

    Source sequence(s)
    CR855375
    UniProtKB/TrEMBL
    A0A8M1NCD6, A4FUN5
    Related
    ENSDARP00000087580.3, ENSDART00000093148.5
    Conserved Domains (1) summary
    pfam06246
    Location:1266
    Isy1; Isy1-like splicing family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    474433..486532 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)