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frmd5b FERM domain containing 5b [ Danio rerio (zebrafish) ]

Gene ID: 569968, updated on 2-Nov-2024

Summary

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Official Symbol
frmd5bprovided by ZNC
Official Full Name
FERM domain containing 5bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060810-165
See related
Ensembl:ENSDARG00000079622 AllianceGenome:ZFIN:ZDB-GENE-060810-165
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
frmd5; im:7161681
Summary
Predicted to be involved in developmental process. Predicted to be located in cytoskeleton and membrane. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with eye movement abnormalities and ataxia. Orthologous to human FRMD5 (FERM domain containing 5). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See frmd5b in Genome Data Viewer
Location:
chromosome: 7
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (30139482..30174839, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (29867770..29903796, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene neuromedin Bb Neighboring gene alpha-kinase 3b Neighboring gene si:ch211-107o10.3 Neighboring gene transmembrane p24 trafficking protein 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in developmental process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
FERM domain-containing protein 5
Names
FERM domain containing 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    30139482..30174839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021477853.2 → XP_021333528.1  FERM domain-containing protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q2G8, E7F1C5
    Related
    ENSDARP00000104250.4, ENSDART00000110409.5
    Conserved Domains (3) summary
    smart00295
    Location:19 → 210
    B41; Band 4.1 homologues
    pfam08736
    Location:309 → 343
    FA; FERM adjacent (FA)
    cl17171
    Location:191 → 294
    PH-like; Pleckstrin homology-like domain

  2. XM_068222630.1 → XP_068078731.1  FERM domain-containing protein 5 isoform X2

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394696.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    101637..143310 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_693389.9 → XP_698481.1  FERM domain-containing protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q2G8, E7F1C5
    Conserved Domains (3) summary
    smart00295
    Location:19 → 210
    B41; Band 4.1 homologues
    pfam08736
    Location:309 → 343
    FA; FERM adjacent (FA)
    cl17171
    Location:191 → 294
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein Strain
Heading Accession and Version

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