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cyth2 cytohesin 2 [ Danio rerio (zebrafish) ]

Gene ID: 569358, updated on 2-Nov-2024

Summary

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Official Symbol
cyth2provided by ZNC
Official Full Name
cytohesin 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-100921-55
See related
Ensembl:ENSDARG00000028800 AllianceGenome:ZFIN:ZDB-GENE-100921-55
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-283b15.4
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within regulation of ARF protein signal transduction. Predicted to be located in cell projection and plasma membrane. Orthologous to human CYTH2 (cytohesin 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See cyth2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (5612565..5639590)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (5712908..5737502)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene microtubule actin crosslinking factor 1b Neighboring gene solute carrier family 52 member 3-2b Neighboring gene si:dkey-283b15.2 Neighboring gene zgc:158689

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Protein kinase C family evolution in jawed vertebrates. Garcia-Concejo A, et al. Dev Biol, 2021 Nov. PMID 34329618
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of ARF protein signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytohesin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    5612565..5639590
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005157846.5 → XP_005157903.1  cytohesin-2

    UniProtKB/TrEMBL
    A0A8M2B4T7, E7F1N2
    Related
    ENSDARP00000117649.1, ENSDART00000140226.2
    Conserved Domains (3) summary
    cd01252
    Location:275 → 394
    PH_GRP1-like; General Receptor for Phosphoinositides-1-like Pleckstrin homology (PH) domain
    pfam00169
    Location:279 → 392
    PH; PH domain
    pfam01369
    Location:78 → 260
    Sec7; Sec7 domain
Nucleotide Protein Strain
Heading Accession and Version

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