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kcp kielin cysteine rich BMP regulator [ Danio rerio (zebrafish) ]

Gene ID: 569039, updated on 12-Sep-2024

Summary

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Official Symbol
kcpprovided by ZNC
Official Full Name
kielin cysteine rich BMP regulatorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070705-443
See related
Ensembl:ENSDARG00000078508 AllianceGenome:ZFIN:ZDB-GENE-070705-443
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-266m15.6
Summary
Orthologous to human KCP (kielin cysteine rich BMP regulator). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See kcp in Genome Data Viewer
Location:
chromosome: 18
Exon count:
48
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (6898350..6982331, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (6941276..7023337, complement)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene protein phosphatase 6, regulatory subunit 2b Neighboring gene uncharacterized LOC101882393 Neighboring gene DnaJ heat shock protein family (Hsp40) member A2b Neighboring gene cadherin-related family member 5 Neighboring gene calumenin b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in positive regulation of BMP signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
kielin/chordin-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    6898350..6982331 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_692402.10 → XP_697494.6  kielin/chordin-like protein

    UniProtKB/TrEMBL
    A0A8N7T8G8, F1Q752
    Related
    ENSDARP00000092299.5, ENSDART00000101525.5
    Conserved Domains (6) summary
    pfam00093
    Location:1803 → 1860
    VWC; von Willebrand factor type C domain
    pfam00094
    Location:1867 → 2016
    VWD; von Willebrand factor type D domain
    pfam01826
    Location:2139 → 2192
    TIL; Trypsin Inhibitor like cysteine rich domain
    pfam08742
    Location:2059 → 2128
    C8; C8 domain
    cl17735
    Location:424 → 480
    VWC; von Willebrand factor type C domain
    cl22861
    Location:38 → 188
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
Nucleotide Protein Strain
Heading Accession and Version

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Molecular Biology Databases
Research Materials