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nyx nyctalopin [ Danio rerio (zebrafish) ]

Gene ID: 568821, updated on 12-Sep-2024

Summary

Official Symbol
nyxprovided by ZNC
Official Full Name
nyctalopinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-061026-3
See related
Ensembl:ENSDARG00000061791 AllianceGenome:ZFIN:ZDB-GENE-061026-3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Acts upstream of or within optokinetic behavior and visual perception. Is expressed in retinal ganglion cell layer; retinal inner nuclear layer; retinal inner plexiform layer; and retinal outer plexiform layer. Used to study congenital stationary night blindness and congenital stationary night blindness 1A. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1A and night blindness. Orthologous to human NYX (nyctalopin). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See nyx in Genome Data Viewer
Location:
chromosome: 9
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (33356770..33360684)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (33544907..33551548)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L8 Neighboring gene DEAD-box helicase 3 X-linked a Neighboring gene calcium/calmodulin-dependent serine protein kinase a Neighboring gene si:dkey-216e24.9 Neighboring gene G protein-coupled receptor 34b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077617.1NP_001071085.1  nyctalopin precursor

    See identical proteins and their annotated locations for NP_001071085.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ201193
    UniProtKB/TrEMBL
    B3DIF3, F6NJ92, Q00P20
    Related
    ENSDARP00000083002.4, ENSDART00000088569.5
    Conserved Domains (4) summary
    smart00082
    Location:332366
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:127311
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:6483
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:227286
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    33356770..33360684
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005167738.5XP_005167795.1  nyctalopin isoform X1

    See identical proteins and their annotated locations for XP_005167795.1

    UniProtKB/TrEMBL
    B3DIF3, F6NJ92, Q00P20
    Conserved Domains (4) summary
    smart00082
    Location:332366
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:127311
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:6483
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:227286
    LRR_8; Leucine rich repeat