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spata13 spermatogenesis associated 13 [ Danio rerio (zebrafish) ]

Gene ID: 568426, updated on 2-Nov-2024

Summary

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Official Symbol
spata13provided by ZNC
Official Full Name
spermatogenesis associated 13provided by ZNC
Primary source
ZFIN:ZDB-GENE-091116-25
See related
Ensembl:ENSDARG00000062837 AllianceGenome:ZFIN:ZDB-GENE-091116-25
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-33c18.3
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in filopodium assembly and lamellipodium assembly. Predicted to be active in cytosol. Orthologous to human SPATA13 (spermatogenesis associated 13). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See spata13 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (21864728..21903440, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (21719554..21758305, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene suppressor of tumorigenicity 14 protein Neighboring gene transmembrane serine protease 7 Neighboring gene C1q and TNF related 9 Neighboring gene transgelin 3b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Duplication and subfunctionalisation of the general transcription factor IIIA (gtf3a) gene in teleost genomes, with ovarian specific transcription of gtf3ab. Rojo-Bartolomé I, et al. PLoS One, 2020. PMID 31999691, Free PMC Article
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in filopodium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in lamellipodium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
spermatogenesis-associated protein 13

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    21864728..21903440 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005162741.5 → XP_005162798.1  spermatogenesis-associated protein 13 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B9P0, E7F6C5
    Related
    ENSDARP00000085685.5, ENSDART00000091252.6
    Conserved Domains (3) summary
    smart00325
    Location:841 → 1020
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01224
    Location:1025 → 1163
    PH_Collybistin_ASEF; Collybistin/APC-stimulated guanine nucleotide exchange factor pleckstrin homology (PH) domain
    cl17036
    Location:747 → 800
    SH3; Src Homology 3 domain superfamily

  2. XM_691753.10 → XP_696845.4  spermatogenesis-associated protein 13 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PX66
    Conserved Domains (3) summary
    smart00325
    Location:813 → 992
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01224
    Location:997 → 1135
    PH_Collybistin_ASEF; Collybistin/APC-stimulated guanine nucleotide exchange factor pleckstrin homology (PH) domain
    cl17036
    Location:719 → 772
    SH3; Src Homology 3 domain superfamily

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395172.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    55908..94624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021473778.2 → XP_021329453.1  spermatogenesis-associated protein 13 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B9P0, E7F6C5
    Conserved Domains (3) summary
    smart00325
    Location:841 → 1020
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01224
    Location:1025 → 1163
    PH_Collybistin_ASEF; Collybistin/APC-stimulated guanine nucleotide exchange factor pleckstrin homology (PH) domain
    cl17036
    Location:747 → 800
    SH3; Src Homology 3 domain superfamily

  2. XM_021473779.2 → XP_021329454.1  spermatogenesis-associated protein 13 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PX66
    Conserved Domains (3) summary
    smart00325
    Location:813 → 992
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01224
    Location:997 → 1135
    PH_Collybistin_ASEF; Collybistin/APC-stimulated guanine nucleotide exchange factor pleckstrin homology (PH) domain
    cl17036
    Location:719 → 772
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein Strain
Heading Accession and Version

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