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hira histone cell cycle regulator a [ Danio rerio (zebrafish) ]

Gene ID: 568076, updated on 2-Nov-2024

Summary

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Official Symbol
hiraprovided by ZNC
Official Full Name
histone cell cycle regulator aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6296
See related
Ensembl:ENSDARG00000013434 AllianceGenome:ZFIN:ZDB-GENE-030131-6296
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb97b07; wu:fb97b07; wu:fi43b08; si:ch211-188g24.3
Summary
Predicted to contribute to nucleosome binding activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within DNA-templated transcription; chromatin organization; and regulation of DNA-templated transcription. Predicted to be located in chromatin. Predicted to be part of HIR complex. Is expressed in telencephalon. Orthologous to human HIRA (histone cell cycle regulator). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See hira in Genome Data Viewer
Location:
chromosome: 5
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (18047198..18072848)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (17543145..17568852)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene activating signal cointegrator 1 complex subunit 2 Neighboring gene ring finger protein 215 Neighboring gene si:dkey-215k6.1 Neighboring gene uncharacterized LOC137495575

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
contributes_to nucleosome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of HIR complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein HIRA
Names
HIR histone cell cycle regulation defective homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    18047198..18072848
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_691386.8 → XP_696478.2  protein HIRA

    UniProtKB/TrEMBL
    A0A8N7URB3, A2CEX6
    Related
    ENSDARP00000119160.1, ENSDART00000132164.2
    Conserved Domains (5) summary
    COG2319
    Location:12 → 382
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:11 → 352
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    pfam07569
    Location:756 → 947
    Hira; TUP1-like enhancer of split
    pfam09453
    Location:448 → 469
    HIRA_B; HIRA B motif
    sd00039
    Location:16 → 65
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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