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wdr26b WD repeat domain 26b [ Danio rerio (zebrafish) ]

Gene ID: 564794, updated on 17-Sep-2024

Summary

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Official Symbol
wdr26bprovided by ZNC
Official Full Name
WD repeat domain 26bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041014-277
See related
Ensembl:ENSDARG00000006812 AllianceGenome:ZFIN:ZDB-GENE-041014-277
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wdr26; fc89f06; fk83a10; wu:fc89f06; wu:fk83a10; si:ch211-153j24.6
Summary
Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in mitochondrion and nucleus. Predicted to be part of GID complex. Orthologous to human WDR26 (WD repeat domain 26). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See wdr26b in Genome Data Viewer
Location:
chromosome: 20
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (46699021..46734051)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (46795284..46830331)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene basic leucine zipper transcription factor, ATF-like Neighboring gene Jun dimerization protein 2b Neighboring gene adenylate cyclase 3b Neighboring gene uncharacterized LOC103909357 Neighboring gene fasciculation and elongation protein zeta 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Wdr26 regulates nuclear condensation in developing erythroblasts. Zhen R, et al. Blood, 2020 Jan 16. PMID 31945154
  2. RES complex is associated with intron definition and required for zebrafish early embryogenesis. Fernandez JP, et al. PLoS Genet, 2018 Jul. PMID 29969449, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of GID complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
WD repeat-containing protein 26
Names
WD repeat domain 26

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001202442.1 → NP_001189371.1  WD repeat-containing protein 26

    See identical proteins and their annotated locations for NP_001189371.1

    Status: VALIDATED

    Source sequence(s)
    AL929435, BX004824
    UniProtKB/Swiss-Prot
    Q5SP67
    Related
    ENSDARP00000132796.1, ENSDART00000167398.2
    Conserved Domains (4) summary
    smart00668
    Location:84 → 143
    CTLH; C-terminal to LisH motif
    COG2319
    Location:258 → 553
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:261 → 553
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:270 → 311
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    46699021..46734051
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068215513.1 → XP_068071614.1  WD repeat-containing protein 26 isoform X2

    Related
    ENSDARP00000036145.6, ENSDART00000029894.8

  2. XM_021468480.2 → XP_021324155.2  WD repeat-containing protein 26 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5SP67.1 GenPept UniProtKB/Swiss-Prot:Q5SP67

Gene LinkOut

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