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lrig3 leucine-rich repeats and immunoglobulin-like domains 3 [ Danio rerio (zebrafish) ]

Gene ID: 564554, updated on 2-Nov-2024

Summary

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Official Symbol
lrig3provided by ZNC
Official Full Name
leucine-rich repeats and immunoglobulin-like domains 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-130530-866
See related
Ensembl:ENSDARG00000079363 AllianceGenome:ZFIN:ZDB-GENE-130530-866
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Is expressed in brain; eye; pharyngeal arch 3-7; presumptive shield; and shield. Orthologous to human LRIG3 (leucine rich repeats and immunoglobulin like domains 3). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
Orthologs
all
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Genomic context

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See lrig3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) Unplaced Scaffold NW_018394371.1 (11448..11796, complement)
RS_2024_08 current GRCz11 (GCF_000002035.6) Unplaced Scaffold NW_018394374.1 (8064..18877)
RS_2024_08 current GRCz11 (GCF_000002035.6) Unplaced Scaffold NW_018394385.1 (10718..11123)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (2978599..3011805)

NW_018394385.1Genomic Context describing neighboring genes

NW_018394374.1Genomic Context describing neighboring genes

NW_018394371.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137489889

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways. Zhao H, et al. Development, 2008 Apr. PMID 18287203, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
leucine-rich repeats and immunoglobulin-like domains protein 3
Names
zmp:0000000863

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110347.1 → NP_001103817.1  leucine-rich repeats and immunoglobulin-like domains protein 3 precursor

    See identical proteins and their annotated locations for NP_001103817.1

    Status: PROVISIONAL

    Source sequence(s)
    EU126152
    Related
    ENSDARP00000099511.4, ENSDART00000110613.4
    Conserved Domains (9) summary
    cd00096
    Location:505 → 581
    Ig; Immunoglobulin domain
    cd05763
    Location:612 → 686
    Ig_1; Subgroup of the immunoglobulin (Ig) superfamily
    smart00408
    Location:703 → 766
    IGc2; Immunoglobulin C-2 Type
    cd00116
    Location:251 → 435
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    pfam07679
    Location:595 → 685
    I-set; Immunoglobulin I-set domain
    sd00031
    Location:64 → 87
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:111 → 134
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:301 → 360
    LRR_8; Leucine rich repeat
    cl15307
    Location:435 → 483
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NW_018394371.1 Reference GRCz11 Primary Assembly

    Range
    11448..11796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 Primary Assembly

Genomic

  1. NW_018394374.1 Reference GRCz11 Primary Assembly

    Range
    8064..18877
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 Primary Assembly

Genomic

  1. NW_018394385.1 Reference GRCz11 Primary Assembly

    Range
    10718..11123
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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