zcchc4 zinc finger, CCHC domain containing 4 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zcchc4provided by ZNC
Official Full Name: zinc finger, CCHC domain containing 4provided by ZNC
Primary source: ZFIN:ZDB-GENE-080204-65
See related: Ensembl:ENSDARG00000104531 AllianceGenome:ZFIN:ZDB-GENE-080204-65
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:172248
Summary: Predicted to enable rRNA (adenine-N6-)-methyltransferase activity. Predicted to be involved in rRNA methylation. Predicted to act upstream of or within methylation. Predicted to be located in nucleus. Predicted to be active in cytoplasm and nucleolus. Orthologous to human ZCCHC4 (zinc finger CCHC-type containing 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (22645324..22670279, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (22524103..22549060, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables rRNA (adenine-N6-)-methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables rRNA (adenine-N6-)-methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
involved_in rRNA methylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within rRNA methylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: rRNA N6-adenosine-methyltransferase ZCCHC4

NP_001107071.1

EC 2.1.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001113599.1 → NP_001107071.1 rRNA N6-adenosine-methyltransferase ZCCHC4

See identical proteins and their annotated locations for NP_001107071.1

Status: PROVISIONAL

Source sequence(s)

BC154611

UniProtKB/TrEMBL

A8WG80

Related

ENSDARP00000138673.1, ENSDART00000164888.2

Conserved Domains (3) summary

pfam06839
Location:27 → 72

zf-GRF; GRF zinc finger

pfam10237
Location:163 → 270

N6-adenineMlase; Probable N6-adenine methyltransferase

pfam12773
Location:371 → 420

DZR; Double zinc ribbon