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abca3b ATP-binding cassette, sub-family A (ABC1), member 3b [ Danio rerio (zebrafish) ]

Gene ID: 564344, updated on 17-Sep-2024

Summary

Official Symbol
abca3bprovided by ZNC
Official Full Name
ATP-binding cassette, sub-family A (ABC1), member 3bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050517-2
See related
Ensembl:ENSDARG00000100524 AllianceGenome:ZFIN:ZDB-GENE-050517-2
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
abca3; si:ch211-155i15.6
Summary
Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in swim bladder. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human ABCA3 (ATP binding cassette subfamily A member 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See abca3b in Genome Data Viewer
Location:
chromosome: 3
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (12585634..12699904)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (12438910..12548455)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene vasorin b Neighboring gene uncharacterized LOC137490486 Neighboring gene cyclin F Neighboring gene uncharacterized LOC108182802 Neighboring gene cytochrome P450, family 2, subfamily K, polypeptide 18 Neighboring gene cytochrome P450, family 2, subfamily k, polypeptide 20

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables lipid transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in lipid transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ATP-binding cassette sub-family A member 3; phospholipid-transporting ATPase ABCA3
Names
ATP-binding cassette, sub-family A (ABC1), member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    12585634..12699904
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021473111.2XP_021328786.1  phospholipid-transporting ATPase ABCA3

    UniProtKB/TrEMBL
    A0A0R4ISK5, A0A8M9Q293
    Conserved Domains (1) summary
    cl28181
    Location:1221695
    AAA; ATPases associated with a variety of cellular activities
  2. XM_021473114.2XP_021328789.1  phospholipid-transporting ATPase ABCA3

    UniProtKB/TrEMBL
    A0A0R4ISK5, A0A8M9Q293
    Conserved Domains (1) summary
    cl28181
    Location:1221695
    AAA; ATPases associated with a variety of cellular activities
  3. XM_068218749.1XP_068074850.1  phospholipid-transporting ATPase ABCA3

  4. XM_009299214.4XP_009297489.1  phospholipid-transporting ATPase ABCA3

    See identical proteins and their annotated locations for XP_009297489.1

    UniProtKB/TrEMBL
    A0A0R4ISK5, A0A8M9Q293
    Related
    ENSDARP00000137256.1, ENSDART00000159252.3
    Conserved Domains (1) summary
    cl28181
    Location:1221695
    AAA; ATPases associated with a variety of cellular activities