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ccar2 cell cycle and apoptosis regulator 2 [ Danio rerio (zebrafish) ]

Gene ID: 564155, updated on 2-Nov-2024

Summary

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Official Symbol
ccar2provided by ZNC
Official Full Name
cell cycle and apoptosis regulator 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-091204-207
See related
Ensembl:ENSDARG00000038302 AllianceGenome:ZFIN:ZDB-GENE-091204-207
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-24n17.5
Summary
Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human CCAR2 (cell cycle and apoptosis regulator 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See ccar2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (2876001..2898724)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (2848789..2871237)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene YKT6 v-SNARE homolog (S. cerevisiae) Neighboring gene DEAD (Asp-Glu-Ala-Asp) box helicase 56 Neighboring gene endoplasmic reticulum aminopeptidase 1a Neighboring gene occludin a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cell cycle and apoptosis regulator protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    2876001..2898724
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005155529.5 → XP_005155586.1  cell cycle and apoptosis regulator protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005155586.1

    UniProtKB/TrEMBL
    A0A8N7UVX0
    Conserved Domains (2) summary
    pfam14443
    Location:309 → 417
    DBC1; DBC1
    pfam14444
    Location:12 → 64
    S1-like; S1-like

  2. XM_005155531.5 → XP_005155588.1  cell cycle and apoptosis regulator protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8M2B1L7, E7FGT1, E9QH28
    Related
    ENSDARP00000115210.1, ENSDART00000140803.4
    Conserved Domains (2) summary
    pfam14443
    Location:309 → 417
    DBC1; DBC1
    pfam14444
    Location:12 → 64
    S1-like; S1-like

  3. XM_005155530.5 → XP_005155587.1  cell cycle and apoptosis regulator protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005155587.1

    UniProtKB/TrEMBL
    A0A8N7UVX0
    Conserved Domains (2) summary
    pfam14443
    Location:309 → 417
    DBC1; DBC1
    pfam14444
    Location:12 → 64
    S1-like; S1-like

  4. XM_687505.8 → XP_692597.4  cell cycle and apoptosis regulator protein 2 isoform X1

    See identical proteins and their annotated locations for XP_692597.4

    UniProtKB/TrEMBL
    A0A8N7UVX0
    Conserved Domains (2) summary
    pfam14443
    Location:309 → 417
    DBC1; DBC1
    pfam14444
    Location:12 → 64
    S1-like; S1-like

  5. XM_068223884.1 → XP_068079985.1  cell cycle and apoptosis regulator protein 2 isoform X3

    Related
    ENSDARP00000155580.1, ENSDART00000192083.1

  6. XM_021479232.2 → XP_021334907.1  cell cycle and apoptosis regulator protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PTS0
    Conserved Domains (2) summary
    pfam14443
    Location:305 → 413
    DBC1
    pfam14444
    Location:8 → 60
    S1-like
Nucleotide Protein
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