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arpp21 cAMP-regulated phosphoprotein, 21 [ Danio rerio (zebrafish) ]

Gene ID: 564134, updated on 2-Nov-2024

Summary

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Official Symbol
arpp21provided by ZNC
Official Full Name
cAMP-regulated phosphoprotein, 21provided by ZNC
Primary source
ZFIN:ZDB-GENE-081104-296
See related
Ensembl:ENSDARG00000061081 AllianceGenome:ZFIN:ZDB-GENE-081104-296
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb474; sb:cb474; wu:fb72d03; si:ch73-92o9.2
Summary
Predicted to enable nucleic acid binding activity. Predicted to be active in cytoplasm. Is expressed in adaxial cell; myotome; and somite. Orthologous to human ARPP21 (cAMP regulated phosphoprotein 21). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See arpp21 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (42886415..42917231)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (43316914..43347794)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene upstream binding protein 1 Neighboring gene programmed cell death 6 interacting protein Neighboring gene microRNA 128-2 Neighboring gene zinc finger TRAF-type containing 1 Neighboring gene doublecortin-like kinase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype. Tonelli F, et al. Matrix Biol, 2020 Aug. PMID 32173581
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cAMP-regulated phosphoprotein 21
Names
cAMP-regulated phosphoprotein, 21kDa
cyclic AMP-regulated phosphoprotein, 21

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    42886415..42917231
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_687493.9 → XP_692585.5  cAMP-regulated phosphoprotein 21 isoform X1

    UniProtKB/TrEMBL
    A0A2R9YJI6, A0A8N7UR40
    Related
    ENSDARP00000126062.1, ENSDART00000151298.3
    Conserved Domains (1) summary
    cd02642
    Location:137 → 197
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...

  2. XM_005159755.5 → XP_005159812.1  cAMP-regulated phosphoprotein 21 isoform X3

    UniProtKB/TrEMBL
    A0A8M2B6J9
    Conserved Domains (1) summary
    cd02642
    Location:137 → 197
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...

  3. XM_005159754.5 → XP_005159811.1  cAMP-regulated phosphoprotein 21 isoform X2

    UniProtKB/TrEMBL
    A0A8M2B6M6
    Related
    ENSDARP00000126087.3, ENSDART00000051724.7
    Conserved Domains (1) summary
    cd02642
    Location:137 → 197
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...

  4. XM_068215328.1 → XP_068071429.1  cAMP-regulated phosphoprotein 21 isoform X4

Nucleotide Protein Strain
Heading Accession and Version

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