rims3 regulating synaptic membrane exocytosis 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rims3provided by ZNC
Official Full Name: regulating synaptic membrane exocytosis 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-060503-788
See related: Ensembl:ENSDARG00000062305 AllianceGenome:ZFIN:ZDB-GENE-060503-788
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-239d6.1
Summary: Predicted to enable transmembrane transporter binding activity. Predicted to be involved in calcium ion-regulated exocytosis of neurotransmitter; modulation of chemical synaptic transmission; and regulation of membrane potential. Predicted to act upstream of or within exocytosis. Predicted to be located in membrane. Predicted to be active in cytoskeleton of presynaptic active zone and presynaptic membrane. Orthologous to human RIMS3 (regulating synaptic membrane exocytosis 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (25155542..25301562, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (25577894..25717340, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables small GTPase binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of presynaptic active zone	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within exocytosis	IEA Inferred from Electronic Annotation more info
involved_in regulation of synaptic vesicle exocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in synaptic vesicle docking	IBA Inferred from Biological aspect of Ancestor more info
involved_in synaptic vesicle priming	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in presynaptic active zone cytoplasmic component	IBA Inferred from Biological aspect of Ancestor more info
is_active_in presynaptic membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: regulating synaptic membrane exocytosis protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001100009.2 → NP_001093479.1 regulating synaptic membrane exocytosis protein 3

Status: PROVISIONAL

Source sequence(s)

BX927077, CR855860

UniProtKB/TrEMBL

A0A8M1NF70

Related

ENSDARP00000094802.2, ENSDART00000104027.3

Conserved Domains (1) summary

cl14603
Location:138 → 282

C2; C2 domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007130.7 Reference GRCz11 Primary Assembly

Range

25155542..25301562 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005170052.5 → XP_005170109.1 regulating synaptic membrane exocytosis protein 3 isoform X1

UniProtKB/TrEMBL

A0A8M2BHF8, A5PMY1

Related

ENSDARP00000144217.1, ENSDART00000175739.2

Conserved Domains (1) summary

cl14603
Location:152 → 296

C2; C2 domain