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inavab innate immunity activator b [ Danio rerio (zebrafish) ]

Gene ID: 563192, updated on 2-Nov-2024

Summary

Official Symbol
inavabprovided by ZNC
Official Full Name
innate immunity activator bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-061103-190
See related
Ensembl:ENSDARG00000070571 AllianceGenome:ZFIN:ZDB-GENE-061103-190
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fk70d05; zgc:153953
Summary
Predicted to be involved in adherens junction maintenance and positive regulation of protein ubiquitination. Human ortholog(s) of this gene implicated in inflammatory bowel disease 29. Orthologous to human INAVA (innate immunity activator). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See inavab in Genome Data Viewer
Location:
chromosome: 11
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (24716790..24756816)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (24478945..24519200)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101886928 Neighboring gene G protein-coupled receptor 25 Neighboring gene arginyl aminopeptidase (aminopeptidase B) Neighboring gene cytochrome b5 reductase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General protein information

Preferred Names
innate immunity activator b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080005.1NP_001073474.1  innate immunity activator b

    See identical proteins and their annotated locations for NP_001073474.1

    Status: PROVISIONAL

    Source sequence(s)
    BC125922
    UniProtKB/TrEMBL
    A0A8N1YZP0, A0JML5
    Related
    ENSDARP00000082173.5, ENSDART00000087740.6
    Conserved Domains (1) summary
    pfam11819
    Location:8136
    DUF3338; Domain of unknown function (DUF3338)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    24716790..24756816
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169303.5XP_005169360.1  innate immunity activator b isoform X1

    See identical proteins and their annotated locations for XP_005169360.1

    UniProtKB/TrEMBL
    A0A8N1YZP0, A0JML5
    Conserved Domains (1) summary
    pfam11819
    Location:8136
    DUF3338; Domain of unknown function (DUF3338)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394820.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    222991..251898
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)