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si:ch211-219a15.4 si:ch211-219a15.4 [ Danio rerio (zebrafish) ]

Gene ID: 563138, updated on 2-Nov-2024

Summary

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Official Symbol
si:ch211-219a15.4provided by ZNC
Official Full Name
si:ch211-219a15.4provided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-308
See related
Ensembl:ENSDARG00000068951 AllianceGenome:ZFIN:ZDB-GENE-060503-308
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable chitin synthase activity. Predicted to be involved in chitin biosynthetic process. Predicted to be located in membrane. Is expressed in fin and scale. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See si:ch211-219a15.4 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (15758328..15768462)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (15793904..15799721)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene si:ch211-264e16.2 Neighboring gene si:ch211-264e16.1 Neighboring gene C1q and TNF related 13 Neighboring gene ubiquitin-conjugating enzyme E2Na

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Chitin is endogenously produced in vertebrates. Tang WJ, et al. Curr Biol, 2015 Mar 30. PMID 25772447, Free PMC Article
  2. Differential roles of the fish chitinous membrane in gut barrier immunity and digestive compartments. Yue Z, et al. EMBO Rep, 2023 Apr 5. PMID 36852962, Free PMC Article
  3. High-throughput transcriptome sequencing reveals the combined effects of key e-waste contaminants, decabromodiphenyl ether (BDE-209) and lead, in zebrafish larvae. Chen L, et al. Environ Pollut, 2016 Jul. PMID 27107256
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables chitin synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chitin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
chitin synthase chs-1; uncharacterized protein LOC563138
XP_017207547.2
XP_021330070.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    15758328..15768462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017352058.3 → XP_017207547.2  chitin synthase chs-1

    UniProtKB/TrEMBL
    A0A8M6YW55
    Related
    ENSDARP00000118024.1, ENSDART00000137554.2
    Conserved Domains (3) summary
    cd04190
    Location:481 → 818
    Chitin_synth_C; C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin
    COG0697
    Location:61 → 237
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
    cl26109
    Location:661 → 1012
    Chitin_synth_2; Chitin synthase

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395336.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    300732..310866
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021474395.2 → XP_021330070.1  chitin synthase chs-1

    UniProtKB/TrEMBL
    A0A8M6YW55
    Conserved Domains (3) summary
    cd04190
    Location:481 → 818
    Chitin_synth_C; C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin
    COG0697
    Location:61 → 237
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
    cl26109
    Location:661 → 1012
    Chitin_synth_2; Chitin synthase
Nucleotide Protein Strain
Heading Accession and Version

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