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rnmt RNA (guanine-7-) methyltransferase [ Danio rerio (zebrafish) ]

Gene ID: 562801, updated on 2-Nov-2024

Summary

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Official Symbol
rnmtprovided by ZNC
Official Full Name
RNA (guanine-7-) methyltransferaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041008-25
See related
Ensembl:ENSDARG00000070553 AllianceGenome:ZFIN:ZDB-GENE-041008-25
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fi09c12; im:6910566; wu:fi09c12; si:ch211-105d11.3
Summary
Predicted to enable RNA binding activity and mRNA 5'-cap (guanine-N7-)-methyltransferase activity. Predicted to be involved in 7-methylguanosine mRNA capping. Predicted to act upstream of or within mRNA processing and methylation. Predicted to be part of mRNA cap methyltransferase RNMT:RAMAC complex. Predicted to be active in nucleus. Orthologous to human RNMT (RNA guanine-7 methyltransferase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See rnmt in Genome Data Viewer
Location:
chromosome: 19
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (12649811..12681730)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (12730283..12762202)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene low density lipoprotein receptor class A domain containing 4a Neighboring gene family with sequence similarity 210 member Aa Neighboring gene uncharacterized LOC137488483 Neighboring gene melanocortin 5a receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables mRNA 5'-cap (guanine-N7-)-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA 5'-cap (guanine-N7-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables mRNA 5'-cap (guanine-N7-)-methyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in 7-methylguanosine mRNA capping IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within 7-methylguanosine mRNA capping IEA
Inferred from Electronic Annotation
more info
  
involved_in 7-methylguanosine mRNA capping ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mRNA cap methyltransferase RNMT:RAMAC complex ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
mRNA cap guanine-N7 methyltransferase
Names
RG7MT1
mRNA (guanine-N(7)-)-methyltransferase
mRNA cap methyltransferase
NP_001038465.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045000.1 → NP_001038465.1  mRNA cap guanine-N7 methyltransferase

    See identical proteins and their annotated locations for NP_001038465.1

    Status: PROVISIONAL

    Source sequence(s)
    AL928820
    UniProtKB/Swiss-Prot
    Q1MTD3
    Related
    ENSDARP00000083350.6, ENSDART00000088917.7
    Conserved Domains (2) summary
    COG0500
    Location:85 → 256
    SmtA; SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]
    pfam03291
    Location:69 → 398
    Pox_MCEL; mRNA capping enzyme

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    12649811..12681730
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q1MTD3.1 GenPept UniProtKB/Swiss-Prot:Q1MTD3

Gene LinkOut

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