dlgap4a discs, large (Drosophila) homolog-associated protein 4a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dlgap4aprovided by ZNC
Official Full Name: discs, large (Drosophila) homolog-associated protein 4aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-080219-51
See related: AllianceGenome:ZFIN:ZDB-GENE-080219-51
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: dlgap4; zgc:171808
Summary: Predicted to enable molecular adaptor activity. Predicted to be involved in regulation of postsynaptic neurotransmitter receptor activity. Predicted to act upstream of or within signaling. Predicted to be active in glutamatergic synapse and postsynaptic specialization. Orthologous to human DLGAP4 (DLG associated protein 4). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: Annotation category: partial on reference assembly
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (42836124..43126132, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (42943521..43233354, complement)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fk85g01.x1 (e-PCR)
- UniSTS:201632

fk71g01.x1 (e-PCR)
- UniSTS:201463

Homology

NCBI Orthologs

Orthologs from OrthoDB

Clone Names

MGC171808

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular adaptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of postsynaptic neurotransmitter receptor activity	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signaling	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in glutamatergic synapse	IBA Inferred from Biological aspect of Ancestor more info
is_active_in postsynaptic specialization	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: discs, large (Drosophila) homolog-associated protein 4a; disks large-associated protein 4

Names: discs, large homolog-associated protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007134.7 Reference GRCz11 Primary Assembly

Range

42836124..43126132 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021470049.1 → XP_021325724.1 disks large-associated protein 4

UniProtKB/TrEMBL

A0A8M9PLE1

Conserved Domains (1) summary

pfam03359
Location:713 → 1034

GKAP; Guanylate-kinase-associated protein (GKAP) protein