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rcn1 reticulocalbin 1, EF-hand calcium binding domain [ Danio rerio (zebrafish) ]

Gene ID: 562671, updated on 2-Nov-2024

Summary

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Official Symbol
rcn1provided by ZNC
Official Full Name
reticulocalbin 1, EF-hand calcium binding domainprovided by ZNC
Primary source
ZFIN:ZDB-GENE-080225-33
See related
Ensembl:ENSDARG00000070006 AllianceGenome:ZFIN:ZDB-GENE-080225-33
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7158588; wu:fa06h02
Summary
Predicted to enable calcium ion binding activity. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including axial mesoderm; chordo neural hinge; epidermis; head; and pectoral fin. Orthologous to human RCN1 (reticulocalbin 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See rcn1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (15818903..15830161, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (15570892..15582358, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene myocyte enhancer factor 2ab Neighboring gene multiple C2 domains, transmembrane 2b Neighboring gene paired box 6b Neighboring gene elongator acetyltransferase complex subunit 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A survey of ancient conserved non-coding elements in the PAX6 locus reveals a landscape of interdigitated cis-regulatory archipelagos. Bhatia S, et al. Dev Biol, 2014 Mar 15. PMID 24440152
  2. Subfunctionalization of duplicated zebrafish pax6 genes by cis-regulatory divergence. Kleinjan DA, et al. PLoS Genet, 2008 Feb. PMID 18282108, Free PMC Article
  3. Evolution of the vertebrate Pax4/6 class of genes with focus on its novel member, the Pax10 gene. Feiner N, et al. Genome Biol Evol, 2014 Jun 19. PMID 24951566, Free PMC Article
  4. Systematic human/zebrafish comparative identification of cis-regulatory activity around vertebrate developmental transcription factor genes. Navratilova P, et al. Dev Biol, 2009 Mar 15. PMID 19073165
  5. Identification and expression of liver-specific genes after LPS challenge in amphioxus: the hepatic cecum as liver-like organ and "pre-hepatic" acute phase response. Wang Y, et al. Funct Integr Genomics, 2011 Mar. PMID 21052758

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
reticulocalbin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    15818903..15830161 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_686046.9 → XP_691138.1  reticulocalbin-1

    UniProtKB/TrEMBL
    A0A8N7TEW4, F1R369
    Related
    ENSDARP00000093139.4, ENSDART00000102363.5
    Conserved Domains (3) summary
    cd00051
    Location:199 → 262
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:161 → 221
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:75 → 132
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein Strain
Heading Accession and Version

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