dph2 diphthamide biosynthesis 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dph2provided by ZNC
Official Full Name: diphthamide biosynthesis 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-030219-100
See related: Ensembl:ENSDARG00000078077 AllianceGenome:ZFIN:ZDB-GENE-030219-100
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: id:ibd5058; zgc:162269
Summary: Predicted to enable transferase activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine. Is expressed in brain; immature eye; somite; and tail bud. Orthologous to human DPH2 (diphthamide biosynthesis 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (41322436..41330126)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (41042363..41050053)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 2-(3-amino-3-carboxypropyl)histidine synthase activity	IEA Inferred from Electronic Annotation more info
contributes_to 2-(3-amino-3-carboxypropyl)histidine synthase activity	ISS Inferred from Sequence or Structural Similarity more info
enables 4 iron, 4 sulfur cluster binding	ISS Inferred from Sequence or Structural Similarity more info
enables iron-sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein histidyl modification to diphthamide	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein histidyl modification to diphthamide	IEA Inferred from Electronic Annotation more info
involved_in protein histidyl modification to diphthamide	IEA Inferred from Electronic Annotation more info
involved_in protein histidyl modification to diphthamide	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of 2-(3-amino-3-carboxypropyl)histidine synthase complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

Names: S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2; diphthamide biosynthesis protein 2; diphtheria toxin resistance protein 2

NP_001082866.1

EC 2.5.1.108

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

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These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.