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zufsp zinc finger containing ubiquitin peptidase 1 [ Danio rerio (zebrafish) ]

Gene ID: 562478, updated on 28-Oct-2024

Summary

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Official Symbol
zufspprovided by ZNC
Official Full Name
zinc finger containing ubiquitin peptidase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-070209-211
See related
Ensembl:ENSDARG00000059983 AllianceGenome:ZFIN:ZDB-GENE-070209-211
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7145879; zgc:158611
Summary
Predicted to enable cysteine-type deubiquitinase activity and metal ion binding activity. Predicted to be located in cytoplasm and nucleus. Orthologous to human ZUP1 (zinc finger containing ubiquitin peptidase 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See zufsp in Genome Data Viewer
Location:
chromosome: 16
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (32184485..32196774)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (32230455..32242741)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor, class C, group 6, member A Neighboring gene karyopherin alpha 5 (importin alpha 6) Neighboring gene RWD domain containing 1 Neighboring gene calcium homeostasis modulator protein 5-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC158611

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger-containing ubiquitin peptidase 1
Names
zinc finger with UFM1-specific peptidase domain
NP_001076474.2
XP_005158409.1
XP_005158410.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083005.2 → NP_001076474.2  zinc finger-containing ubiquitin peptidase 1

    Status: VALIDATED

    Source sequence(s)
    CT027708
    UniProtKB/TrEMBL
    A0A8M1NC71, F1QAX5
    Related
    ENSDARP00000078444.4, ENSDART00000084009.6
    Conserved Domains (2) summary
    pfam05283
    Location:71 → 149
    MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin
    pfam07910
    Location:363 → 581
    Peptidase_C78; Peptidase family C78

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    32184485..32196774
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005158352.5 → XP_005158409.1  zinc finger-containing ubiquitin peptidase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B5A2
    Conserved Domains (2) summary
    pfam05283
    Location:71 → 149
    MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin
    pfam07910
    Location:343 → 561
    Peptidase_C78; Peptidase family C78

  2. XM_005158353.5 → XP_005158410.1  zinc finger-containing ubiquitin peptidase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M2B580
    Conserved Domains (2) summary
    pfam05283
    Location:71 → 149
    MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin
    pfam07910
    Location:307 → 525
    Peptidase_C78; Peptidase family C78
Nucleotide Protein Strain
Heading Accession and Version

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