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tbrg4 transforming growth factor beta regulator 4 [ Danio rerio (zebrafish) ]

Gene ID: 562388, updated on 12-Sep-2024

Summary

Official Symbol
tbrg4provided by ZNC
Official Full Name
transforming growth factor beta regulator 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-091020-8
See related
Ensembl:ENSDARG00000074807 AllianceGenome:ZFIN:ZDB-GENE-091020-8
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable RNA binding activity. Predicted to be involved in mitochondrial RNA processing and regulation of mitochondrial mRNA stability. Predicted to be active in mitochondrial matrix and ribonucleoprotein granule. Orthologous to human TBRG4 (transforming growth factor beta regulator 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See tbrg4 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (27660006..27677960, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (27725383..27743394, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene GLI pathogenesis-related 2, like Neighboring gene NAC alpha domain containing Neighboring gene STEAP family member 4 Neighboring gene zinc finger protein 804B

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in mitochondrial RNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of mitochondrial mRNA stability IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of mitochondrial mRNA stability IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
is_active_in ribonucleoprotein granule IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein TBRG4; FAST kinase domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    27660006..27677960 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_685771.9XP_690863.4  FAST kinase domain-containing protein 4

    UniProtKB/TrEMBL
    A0A8N7UVV2, E7F3K7
    Related
    ENSDARP00000122165.1, ENSDART00000145991.3
    Conserved Domains (3) summary
    smart00952
    Location:563620
    RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
    pfam06743
    Location:370437
    FAST_1; FAST kinase-like protein, subdomain 1
    pfam08368
    Location:454535
    FAST_2; FAST kinase-like protein, subdomain 2