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tnfsf10l3 tumor necrosis factor (ligand) superfamily, member 10 like 3 [ Danio rerio (zebrafish) ]

Gene ID: 562262, updated on 2-Nov-2024

Summary

Official Symbol
tnfsf10l3provided by ZNC
Official Full Name
tumor necrosis factor (ligand) superfamily, member 10 like 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-070606-1
See related
Ensembl:ENSDARG00000032746 AllianceGenome:ZFIN:ZDB-GENE-070606-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
dl1b
Summary
Predicted to enable cytokine activity. Predicted to be involved in cell surface receptor signaling pathway; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of extrinsic apoptotic signaling pathway. Predicted to act upstream of or within immune response. Predicted to be located in membrane. Predicted to be active in extracellular space. Is expressed in anterior lateral line neuromast; posterior lateral line neuromast; and posterior lateral line primordium. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See tnfsf10l3 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (30701902..30714555, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (30665207..30677860, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene si:dkey-22f5.9 Neighboring gene uncharacterized LOC137488829 Neighboring gene chloride channel, voltage-sensitive 5a Neighboring gene xrcc1 N-terminal domain containing 1 Neighboring gene transient receptor potential cation channel subfamily C member 2b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of canonical NF-kappaB signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of extrinsic apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tumor necrosis factor (ligand) superfamily, member 10 like 3
Names
TNFSF10-3
death ligand 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042713.1NP_001036178.1  tumor necrosis factor (ligand) superfamily, member 10 like 3

    See identical proteins and their annotated locations for NP_001036178.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ812113
    UniProtKB/TrEMBL
    B3DHP1, F6P519, Q0PKX9
    Related
    ENSDARP00000112169.2, ENSDART00000128011.3
    Conserved Domains (1) summary
    pfam00229
    Location:158286
    TNF; TNF(Tumour Necrosis Factor) family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    30701902..30714555 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)