cenpt centromere protein T [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cenptprovided by ZNC
Official Full Name: centromere protein Tprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-3256
See related: Ensembl:ENSDARG00000091271 AllianceGenome:ZFIN:ZDB-GENE-030131-3256
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc31h11; fc75c05; wu:fc31h11; wu:fc75c05; si:ch211-225g23.1
Summary: Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be involved in chromosome segregation and mitotic cell cycle. Predicted to act upstream of or within kinetochore assembly. Predicted to be located in kinetochore and nucleus. Used to study Seckel syndrome. Orthologous to human CENPT (centromere protein T). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (6394901..6418054)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (6289371..6312546)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in chromosome segregation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within kinetochore assembly	IEA Inferred from Electronic Annotation more info
involved_in mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in kinetochore	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_017353030.2 → XP_017208519.1 centromere protein T isoform X3

UniProtKB/TrEMBL

A0A8M6Z3Y5
XM_017353029.2 → XP_017208518.1 centromere protein T isoform X1

UniProtKB/TrEMBL

A0A8M6YX66
XM_005161005.4 → XP_005161062.1 centromere protein T isoform X2

UniProtKB/TrEMBL

A0A8M2B862, E9QIT3

Conserved Domains (2) summary

pfam16171
Location:5 → 258

CENP-T_N; Centromere kinetochore component CENP-T N-terminus

cl23735
Location:809 → 904

H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...