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gra granulito [ Danio rerio (zebrafish) ]

Gene ID: 561889, updated on 2-Nov-2024

Summary

Official Symbol
graprovided by ZNC
Official Full Name
granulitoprovided by ZNC
Primary source
ZFIN:ZDB-GENE-081022-203
See related
Ensembl:ENSDARG00000078754 AllianceGenome:ZFIN:ZDB-GENE-081022-203
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:195256; zgc:195266
Summary
Predicted to enable eukaryotic initiation factor 4E binding activity. Predicted to be involved in negative regulation of translational initiation. Predicted to act upstream of or within negative regulation of translation. Located in P granule. Is expressed in blastomere and primordial germ cell. Orthologous to human C8orf88 (chromosome 8 open reading frame 88). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See gra in Genome Data Viewer
Location:
chromosome: 16
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (16222394..16226220, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (16314417..16318243, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene stathmin 2a Neighboring gene uridine phosphorylase 1 Neighboring gene RNA binding motif protein 12Bb Neighboring gene uncharacterized LOC110438014

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables eukaryotic initiation factor 4E binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables eukaryotic initiation factor 4E binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in P granule IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein C8orf88 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100948.2NP_001094418.2  uncharacterized protein C8orf88 homolog

    See identical proteins and their annotated locations for NP_001094418.2

    Status: VALIDATED

    Source sequence(s)
    BX321920, EH550198
    UniProtKB/TrEMBL
    B3DKF4, B3DKG4, F6NNX3
    Related
    ENSDARP00000098356.2, ENSDART00000108965.4
    Conserved Domains (1) summary
    pfam05456
    Location:84120
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    16222394..16226220 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)