unm_sa1614 un-named sa1614 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: unm_sa1614provided by ZNC
Official Full Name: un-named sa1614provided by ZNC
Primary source: ZFIN:ZDB-GENE-120411-1
See related: Ensembl:ENSDARG00000002607 AllianceGenome:ZFIN:ZDB-GENE-120411-1
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: asap1
Summary: Predicted to enable GTPase activator activity. Predicted to act upstream of or within positive regulation of GTPase activity. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 11

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (26476213..26564530)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (26238556..26324228)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTPase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of GTPase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

Names: ArfGAP with SH3 domain, ankyrin repeat and PH domain 1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007122.7 Reference GRCz11 Primary Assembly

Range

26476213..26564530

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005169326.5 → XP_005169383.1 arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1

UniProtKB/TrEMBL

A0A8M2BGM9

Conserved Domains (8) summary

cd07604
Location:34 → 248

BAR_ASAPs; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing proteins

cd11821
Location:965 → 1017

SH3_ASAP; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing proteins

cd00204
Location:585 → 673

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

cd13251
Location:300 → 406

PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain

pfam00169
Location:309 → 395

PH; PH domain

pfam01412
Location:423 → 540

ArfGap; Putative GTPase activating protein for Arf

pfam12796
Location:551 → 651

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:551 → 582

ANK; ANK repeat [structural motif]
XM_685280.9 → XP_690372.5 arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X3

UniProtKB/TrEMBL

A0A8N7TB41

Related

ENSDARP00000094283.3, ENSDART00000103507.5

Conserved Domains (8) summary

cd07604
Location:34 → 248

BAR_ASAPs; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing proteins

cd11821
Location:961 → 1013

SH3_ASAP; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing proteins

cd00204
Location:581 → 669

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

cd13251
Location:296 → 402

PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain

pfam00169
Location:305 → 391

PH; PH domain

pfam01412
Location:419 → 536

ArfGap; Putative GTPase activating protein for Arf

pfam12796
Location:547 → 647

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:547 → 578

ANK; ANK repeat [structural motif]
XM_068224347.1 → XP_068080448.1 arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X2